MeSH tree: C04.557.450.795.550.660
It's one of the cruelest ironies in health and medicine. Pediatric sarcomas are among the rarest yet most aggressive forms of childhood cancer and some of the hardest to cure. Whereas many adult cancers are now treatable ...
Sep 10, 2026
0
3
Rhabdomyosarcomas are a rare form of cancer; however, the disease is responsible for about 60% of all soft-tissue sarcomas in children. Rhabdomyosarcomas are aberrant, malignant forms of muscle tissue. Early detection of ...
Aug 25, 2026
0
5
New insights into why some children with rhabdomyosarcoma (RMS) develop aggressive disease despite being classified as non-high-risk have been uncovered. The discovery could help clinicians identify children with potentially ...
Aug 19, 2026
0
5
A cancer researcher at the University of Houston is reporting what makes malignant soft tissue cancer grow in children, identifying key mechanisms and molecular targets to prevent tumor progression in patients in future therapies ...
Jun 9, 2026
0
6
Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene expression. While progress ...
Mar 18, 2026
0
3
Researchers at Children's Hospital Los Angeles have discovered a key difference between the two main types of rhabdomyosarcoma—paving the way for more targeted treatments.
Jul 23, 2025
0
14
An artificial intelligence (AI)-based model accurately classified pediatric sarcomas using digital pathology images alone, according to results presented at the American Association for Cancer Research (AACR) Annual Meeting, ...
Apr 29, 2025
0
12
University of Queensland research using natural killer cells may lead to the first new treatment for a devastating childhood cancer in 40 years. Associate Professor Fernando Guimaraes, a Principal Research Fellow from UQ's ...
Feb 11, 2025
0
14
Bone pain. Joint pain. Bone swelling. These are symptoms that about 1,000 people in the United States begin to feel each year shortly before being diagnosed with osteosarcoma, a type of cancer that starts in the bones. Although ...
Jan 17, 2025
0
33
Hereditary changes in genes are often the cause of rare diseases. For example, disease-causing gene variants (PVs) in the HRAS gene cause Costello syndrome and PVs in the KRAS gene cause Noonan syndrome and cardio-facio-cutaneous ...
Sep 26, 2024
0
40
