MeSH tree: C04.700.600
Children born with a pathogenic variant in the TP53 gene, known as Li-Fraumeni syndrome, have a markedly increased risk of developing various types of cancer, often at a young age. Therefore, they undergo regular surveillance ...
Aug 5, 2026
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Screening people with the rare, inherited cancer-causing condition Li-Fraumeni syndrome (LFS) brings both medical and economic benefits to patients and health care systems, according to research to be presented to the annual ...
Jun 15, 2026
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In a prospective validation study, researchers at The University of Texas MD Anderson Cancer Center have demonstrated that a new mathematical model called LFSPRO was effective in supporting genetic counselor decision-making ...
Apr 23, 2026
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An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, change what they do and ...
Mar 1, 2026
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Li-Fraumeni syndrome is a rare hereditary disease that significantly increases the risk of developing cancer. Almost all affected individuals receive a cancer diagnosis at least once in their lifetime. A new study suggests ...
Jan 26, 2026
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Little is known about what causes ovarian cancer, and there is no way to detect it early yet. About 75% of the time when someone is diagnosed with ovarian cancer, it has already progressed to stage 3 or stage 4, which means ...
Jun 25, 2025
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A case in which a sperm donor was later found to be carrying a cancer-causing pathogenic variant in his gametes has highlighted the problems of regulating gamete donation at the European and international level.
May 23, 2025
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QIMR Berghofer-led research has shown that new advanced computational prediction tools can improve the accuracy of genetic testing for families affected by an inherited condition that significantly increases their risk of ...
Apr 29, 2025
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People with the rare Li-Fraumeni syndrome (LFS) have a high risk of developing cancer. Almost all those affected will develop cancer once, and in many cases several times, during their lifetime. LFS is a hereditary disease ...
Mar 13, 2025
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Cancer in children and adolescents is rare. Nevertheless, malignant diseases are still one of the most common causes of death in this age group. Survivors of childhood or adolescent cancer often suffer chronic health problems ...
Dec 30, 2024
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