MeSH tree: C10.551.775.500.750
A scientist at Cincinnati Children's who has hunted for decades for ways to shrink the painful and disfiguring nerve tumors caused by neurofibromatosis type 1 (NF1) has made a new breakthrough in the quest. Nancy Ratner, ...
Sep 2, 2026
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A research team from the Germans Trias i Pujol Research Institute (IGTP) has developed a new experimental model based on induced pluripotent stem cells (iPSCs) that makes it possible to reproduce in the laboratory the progression ...
Jun 22, 2026
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A new study delving into the genetic drivers of a rare and aggressive childhood cancer called Malignant Peripheral Nerve Sheath Tumor (MPNST) has revealed metabolic frailties in the cancer cells that might be exploited to ...
Aug 19, 2025
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An international study has shown that a drug called selumetinib can reduce the pain and size of tumors caused in adults by neurofibromatosis type 1 (NF1), a rare genetic disease for which there is currently no effective pharmacological ...
Jun 25, 2025
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The Hereditary Cancer research group from the Germans Trias i Pujol Research Institute (IGTP) has led an international collaboration that has allowed the genomic characterization of the most commonly used cell lines derived ...
Apr 14, 2023
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Neurofibromatosis type 1 (NF1) is a common genetic condition, affecting 1 in 3,000 individuals, and people with NF1 are at greater risk of developing a rare, aggressive form of cancer. Diagnosing malignant peripheral nerve ...
Jan 4, 2023
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