MeSH tree: C10.562
An international study has shown that a drug called selumetinib can reduce the pain and size of tumors caused in adults by neurofibromatosis type 1 (NF1), a rare genetic disease for which there is currently no effective pharmacological ...
Jun 25, 2025
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Despite what was previously thought, new research has shown that genetic changes alone cannot explain why and where tumors grow in those with the genetic condition neurofibromatosis type 1 (NF-1). Understanding more about ...
Feb 25, 2025
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A multicenter collaboration has identified a potential new treatment for an aggressive sarcoma arising in the nerves. The findings have been published in the journal Clinical Cancer Research.
Jan 28, 2025
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A new report describes a promising approach to studying neurofibromatosis type 1 (NF1), a genetic condition with limited treatment options. The condition causes a number of different cancerous and non-cancerous tumors to ...
Aug 22, 2024
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Port wine stains—capillary malformations on the skin—are the most visible manifestation of Sturge-Weber syndrome. However, up to 60% of babies with birthmarks in high-risk locations (forehead and upper eyelid) also have capillary ...
Jun 27, 2024
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Neurogenetic disorders, such as neurofibromatosis type 1 (NF1), are diseases caused by a defect in one or more genes, which can sometimes result in cognitive and motor impairments. Better understanding the neural underpinning ...
A study in mice by researchers at the School of Medicine indicates that brain injury can lead to brain tumors in susceptible individuals. For this study, they used mice that model people with neurofibromatosis type 1 (NF1), ...
May 9, 2024
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A drug used to treat children with epilepsy prevents brain tumor formation and growth in two mouse models of neurofibromatosis type 1 (NF1), according to a study by researchers at Washington University School of Medicine ...
Apr 15, 2024
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Researchers from the Germans Trias i Pujol Research Institute (IGTP) have made progress in exploring potential treatments for skin tumors associated with neurofibromatosis type 1. Their findings in cell models have been published ...
Feb 13, 2024
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A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs)—soft tissue tumors that are stubbornly resistant to chemotherapy and radiation—according to a laboratory study ...
Jan 31, 2024
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