Nucleic Acids, Nucleotides, and Nucleosides: News and Research on Decitabine

MeSH tree: D13.570.800.286.300.500

Genomic tug of war could boost cancer therapy

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant ...

Epigenetically acting drugs could support cancer immunotherapy

Epigenetically active drugs enable the cell to read parts oft he genome that were previously blocked and inaccessible. This leads to the formation of new mRNA transcripts and also new proteins, as scientists from the German ...

Epigenetic drugs in the mission to beat rare cancers

Only one in 100,000 people suffer from a pheochromocytoma, a tumor of the adrenal gland. If the tumor has already metastasized, a radioactive compound can be used to detect malignant cells that have spread to other parts ...

New optimism on myelodysplastic syndromes

Physician scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have published a review in the Journal of the American Medical Association that clarifies current treatment ...

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