MeSH tree: C18.452.845
New research from Washington University School of Medicine in St. Louis adds to growing evidence that helping brain cells break down and eliminate their own cellular waste is a promising treatment strategy for a variety of ...
Mar 31, 2026
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The symptom profiles of different neurodegenerative diseases often overlap, and diagnosing age-related cognitive symptoms is complex. A patient may have multiple overlapping disease processes in the brain at the same time, ...
Mar 31, 2026
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A landmark research paper for the first time maps the genetics of how individual regions of the brain age—and why some of those regions are the very ones most ravaged by Alzheimer's and dementia. Published in the journal ...
Mar 26, 2026
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What has long been interpreted as permanent and irreversible vascular damage may not be exclusively so. In people with Down syndrome—one of the most robust populations for studying Alzheimer's disease due to the near-universal ...
Mar 19, 2026
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People with Alzheimer's disease often have other neurodegenerative conditions as well, including a less-understood disorder called frontotemporal lobar degeneration (FTLD). While a precise diagnosis of FTLD has only been ...
Mar 16, 2026
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Loss of communication can be among the most devastating symptoms for patients with paralysis. A new study by investigators from Mass General Brigham Neuroscience Institute and Brown University describes an investigational ...
Mar 16, 2026
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In a phase 2b clinical trial, an investigational oral therapy called PrimeC was found to be safe and well tolerated in people living with amyotrophic lateral sclerosis (ALS), with exploratory findings suggesting target engagement ...
Mar 16, 2026
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Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) belong to a spectrum of neurodegenerative diseases with overlapping symptoms, characterized by muscle wasting, paralysis, dementia, and other serious impairments. ...
Mar 12, 2026
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Researchers at VIB and Antwerp University have identified a major genetic risk factor for a rare form of frontotemporal dementia. The discovery, published today in Nature Genetics, provides a biological entry point for a ...
Mar 12, 2026
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A Lawrence Livermore National Laboratory (LLNL)-led team of scientists and computational engineers using one of the largest electronic health record datasets ever assembled for ALS has identified several existing medications ...
Mar 11, 2026
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