MeSH tree: C23.550.362
Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive ...
Jun 26, 2023
0
133
Healthy cells work hard to maintain the integrity of our DNA, but occasionally, a chromosome can get separated from the others and break apart during cell division. The tiny fragments of DNA then get reassembled in random ...
Jun 15, 2023
0
54
A graduate student's curiosity has uncovered a previously unknown link between two important hallmarks of cancer: chromosomal instability and epigenetic alterations.
Jun 7, 2023
0
173
Chromosomal errors are a hallmark of cancer cells. Defects in the genome derived from the incorrect separation of chromosomes (and the DNA packed within) in each division of cells drive tumor growth and resistance to therapy.
Apr 24, 2023
0
45
Genomic profiling of patients who were treated for colorectal cancer at a major U.S. cancer center showed that patients with African ancestry had fewer actionable mutations than patients with European ancestry and were less ...
Apr 17, 2023
0
41
Researchers at Tel Aviv University warn that CRISPR therapeutics can damage the genome. They caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover ...
Jul 25, 2022
0
464
Brain metastasis is one of the most common causes of cancer-related deaths and occurs very frequently in patients with advanced melanoma. Although new immunotherapies are effective in some patients with melanoma brain metastases, ...
Jul 16, 2022
0
177
