MeSH tree: D27.505.519.389.870
Aromatase inhibitors (AIs) are a cornerstone of adjuvant therapy for hormone receptor–positive breast cancer, significantly reducing recurrence and mortality. However, by suppressing estrogen production, AIs accelerate bone ...
Feb 10, 2026
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The investigational, oral selective estrogen receptor degrader (SERD) giredestrant given as an adjuvant therapy showed significant improvement in invasive disease-free survival (iDFS) compared with the current standard-of-care ...
Dec 10, 2025
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In an international study led by UCLA, researchers have shown that giredestrant, a next-generation oral selective estrogen receptor antagonist and degrader (SERD), when given as an adjuvant therapy for early-stage (1–3) hormone ...
Dec 10, 2025
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About 50% of menopausal women experience genitourinary syndrome of menopause (GSM) that involves changes to the genitals, including the vagina, urethra and bladder. When estrogen levels drop during menopause, it can cause ...
Oct 22, 2025
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Hormone modulating therapy (HMT) used for the treatment of breast cancer was associated with a 7% lower risk of developing Alzheimer's disease and related dementias later in life, according to a new study published in JAMA ...
Jul 16, 2024
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A new study suggests that certain drugs commonly used to treat enlarged prostate may also decrease the risk for dementia with Lewy bodies (DLB). This observational finding may seem surprising, but it mirrors previous work ...
Jun 19, 2024
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Many breast cancer survivors take a hormonal drug after cancer treatment to stave off a recurrence, but new research suggests thesedrugs may be less effective in women who are obese.
Oct 18, 2023
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Research published in the Journal of Internal Medicine indicates that SARS-CoV-2 infection may worsen lower urinary tract symptoms (LUTS) in men.
Oct 18, 2023
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For roughly 80% of breast cancer survivors, treatment doesn't end with surgery, radiation and chemotherapy. Instead, for the next five to 10 years, doctors recommend that they take medication to block sex hormones, which ...
Aug 28, 2023
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Retrospective analyses of epidemiologic data have repeatedly shown that COVID-19 mortality is higher in males compared to females. However, the underlying factors mediating sex-specific disease outcome were largely unknown.
Aug 14, 2023
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