Pharmacologic Actions: News and Research on Viral Protease Inhibitors

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Switching to integrase inhibitors from protease inhibitors is associated with new diabetes risk in people with HIV

Diabetes mellitus affects more than 10% of people with HIV, and its incidence is rising as the population ages, according to the National Institutes of Health. Antiretroviral therapies that treat HIV by blocking specific ...

Mar 30, 2026

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Exploratory analysis associates HIV drug abacavir with elevated cardiovascular disease risk in large global trial

Current or previous use of the antiretroviral drug (ARV) abacavir was associated with an elevated risk of major adverse cardiovascular events (MACE) in people with HIV, according to an exploratory analysis from a large international ...

Jul 23, 2024

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Heart attack risk increased among people with HIV and hepatitis C as they aged

As people with HIV age, their risk of heart attack increases far more if they also have untreated hepatitis C virus, even if their HIV is treated, according to new research published today in the Journal of the American Heart ...

Sep 21, 2022

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