MeSH tree: D04.615.723.795.576
The production, distribution, and consumption of illegal opioids create problems for public health and safety in many countries. Overdose rates are particularly high in Canada and the United States, which experienced three ...
Feb 24, 2026
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U.S. overdose deaths fell through most of last year, suggesting a lasting improvement in an epidemic that had been worsening for decades.
Jan 14, 2026
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Kids with broken or sprained limbs don't need oral opioids to treat their pain, according to newly published findings from a cross-Canada study by pediatric emergency researchers. The study is published in JAMA.
Jan 8, 2026
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A preclinical study uncovered a new gene therapy that targets pain centers in the brain while eliminating the risk of addiction from narcotics treatments, a breakthrough which could provide hope for the more than 50 million ...
Jan 7, 2026
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A decline in religious participation among middle-aged, less educated white Americans may have played a role in the widely noted increases in "deaths of despair," a new study finds.
Dec 18, 2025
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New Zealand's mainstay drug law turned 50 this year—yet we still don't have a clear, comprehensive picture of the social harms different drugs pose.
Nov 20, 2025
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Efforts to promote safer opioid prescribing in Canada appear to be having an effect, as new research in the Canadian Medical Association Journal shows a decrease in opioid dispensing between 2018 and 2022.
Oct 27, 2025
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When older adults living in nursing homes are prescribed the pain medicine tramadol alongside certain antidepressants, their risk of seizures may go up, according to a study published in Neurology. While this study found ...
Oct 8, 2025
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Nitazenes—a class of highly potent synthetic opioids—are rapidly emerging as a major contributor to the overdose crisis, according to a Pain Medicine review published today by authors from Vanderbilt University Medical Center ...
Sep 16, 2025
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Deaths following opioid use in England and Wales have nearly doubled in the last decade, with 22.9 deaths per million people in 2012, and 43.8 deaths per million people in 2023. But the true number is likely higher because ...
Sep 16, 2025
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