250-year-old drug enters clinical trial as potential treatment for deadly pancreatic cancer
Researchers in Sweden are testing a 250-year-old medicine in patients with one of the world's deadliest cancers.
Oct 14, 2025
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Polycyclic Compounds: News and Research on Cardenolides
MeSH tree: D04.210.500.155.580.130
Active ingredient from red foxglove helps with heart failure, clinical study confirms
Digitalis has been used to treat heart failure for more than 200 years. The drug digitoxin also belongs to this group of active ingredients known as cardiac glycosides.
Aug 29, 2025
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Non-antibiotic drugs can also disrupt the microbiome
Non-antibiotic drugs can alter the microbiome and increase the risk of gut infections in surprising ways, a new Nature study shows.
Aug 6, 2025
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240-year-old drug could save UK NHS £100 million a year treating common heart rhythm disorder
A 240-year-old drug called digoxin could save the National Health Service (NHS) at least £100 million each year when treating older patients with atrial fibrillation and heart failure. This was compared to usual treatment ...
Jan 31, 2025
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Proof-of-concept study dissolves clusters of breast cancer cells to prevent metastases
Certain tumor types do not remain at their point of origin but spread throughout the body and form metastases. This is because the primary tumor continuously releases cancer cells into the blood. These circulating tumor cells ...
Jan 24, 2025
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Study offers hope of a new treatment for rare endometrial cancer
A team of researchers at the University of Alberta has found that digoxin, a drug widely used to treat congestive heart failure, is an effective therapy for a rare and aggressive form of endometrial cancer.
Sep 16, 2024
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Off-the-shelf wearable trackers provide clinically-useful information for patients with heart disease
A study published in Nature Medicine examined if a commercially-available fitness tracker and smartphone could continuously monitor the response to medications, and provide clinical information similar to in-person hospital ...
Jul 15, 2024
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Rapid drug test to provide patients with better care
Teams at two of Melbourne's leading research and medical institutes are developing high-tech solutions to rapidly test for drugs and better treat patients presenting to hospital.
Jul 5, 2024
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Digoxin shows promise in enhancing post-surgery survival for infants with certain heart defects
A strong, rhythmic pulse is a lifelong companion for those with a healthy heart. But for about 1% of babies born in the U.S. every year, developmental heart problems compromise that steady beat.
Dec 29, 2023
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Atrial fibrillation diagnosis associated with increased risk of memory decline
Atrial fibrillation (AF) diagnosis was associated with a 45% increased risk of mild cognitive impairment (MCI) among a cohort of 4.3 million individuals in the UK, according to a new study published in JACC: Advances. These ...
Oct 25, 2023
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