MeSH tree: E02.095.601
A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has shown that a single injection of an oncolytic virus—a genetically modified virus that selectively infects and destroys cancer cells—can ...
Feb 11, 2026
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A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect ...
Oct 8, 2025
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Researchers at Columbia Engineering have built a cancer therapy that makes bacteria and viruses work as a team. In a study published in Nature Biomedical Engineering, the Synthetic Biological Systems Lab shows how their system ...
Aug 15, 2025
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The herpes simplex virus type 1 (HSV-1), which affects almost two‑thirds of the world's population and is generally associated with oral herpes, may cause painful cold sores or fever blisters around the mouth.
Jul 8, 2025
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A study appearing in Nature investigated the role of astrocytes, an abundant cell type in the brain, in regulating an immune response against glioblastoma (GBM)—a highly aggressive brain cancer. Researchers found a subset ...
May 26, 2025
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Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, offering a unique potential to selectively target malignant cells while sparing normal tissues. However, the immunosuppressive ...
Aug 6, 2024
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Northwestern Medicine scientists have discovered that an attenuated (weakened) virus can help eliminate cancer in mice. In addition, mice that were treated with this virus were more resistant to developing tumors later in ...
Jun 11, 2024
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In an advance that could transform bladder cancer treatment, a novel combination of cretostimogene grenadenorepvec and pembrolizumab has shown remarkable efficacy in patients with Bacillus Calmette-Guérin (BCG)-unresponsive ...
Jun 6, 2024
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A multi-institutional team of Chinese microbiologists and pharmacologists has developed a novel way to fight cancerous tumors. Called ONCOTECH, it combines oncolytic virotherapy and adoptive T cell therapy for treatment of ...
