Urogenital Diseases: News and Research on Polycystic Kidney, Autosomal Dominant

MeSH tree: C12.050.351.968.419.403.875.500

Single-dose base editing corrects PKD1 mutation and extends survival in ADPKD preclinical models

Mayo Clinic researchers have developed a promising gene-editing therapy that directly corrects a genetic mutation responsible for autosomal dominant polycystic kidney disease (ADPKD), the most common inherited kidney disorder.

Jan 29, 2026

0

12

Major complications seen in 7% of patients with ADPKD undergoing nephrectomy

Major complications occur in 7.0% of patients undergoing nephrectomy with a diagnosis of autosomal dominant polycystic kidney disease (ADPKD), according to a study published online Dec. 17 in Urology Practice.

Dec 23, 2025

0

10