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Nephrology news

'Toxic' molecule may play vital role in gene regulation and development

A molecule once thought to be a harmful metabolic byproduct may play a crucial role in early development and gene regulation, according to a new study published in Nature that challenges decades of biochemical assumptions. ...

A brief kidney crisis in childhood can cast a long shadow over health for years afterward

Acute kidney injury (AKI) is a condition in which the kidneys suddenly lose their ability to filter waste from the blood. Developing within hours or days, AKI can cause dangerous waste accumulation and disrupt the body's ...

Common asthma drug shows promise for reversing fatty liver

MUSC researchers are tackling MASH, or metabolic dysfunction-associated steatohepatitis, a liver disease affecting hundreds of millions worldwide. It is also a leading cause of liver transplantation, yet treatment options ...

Longer dialysis times associated with better survival

For adults undergoing maintenance in-center hemodialysis, longer dialysis times are associated with better survival, according to a study published in the June issue of Kidney International Reports.

Contrast agents in imaging—do they really harm the kidneys?

"Contrast harms the kidneys"—this belief has been present among patients for years, and sometimes also among physicians. In clinical practice, it may raise concerns about imaging examinations and procedures that use contrast ...

New tool predicts graft failure after kidney transplant

Researchers at The Johns Hopkins Medicine say they have developed a new electronic medical records-based tool that should help doctors predict which patients are most at risk of losing a transplanted kidney graft.

Congenital heart disease mutation linked to kidney damage

Biomedical engineers at Duke University have shown that a genetic mutation that causes congenital heart disease also contributes to kidney damage and developmental defects. Identifying this early cause of kidney damage could ...

Study uncovers glomerular disease outcomes across the lifespan

New research reveals that contrary to conventional belief, primary glomerular diseases are not necessarily benign for children and young adults. In fact, some subsets of children and young adults may experience faster kidney ...

Marker that predicts cell death in kidneys identified

When the kidneys are damaged—after surgery, cardiac arrest, or as a side effect of certain medications—doctors often face one crucial question: Will the kidneys recover, or is the damage permanent?