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Nephrology news

'Toxic' molecule may play vital role in gene regulation and development

A molecule once thought to be a harmful metabolic byproduct may play a crucial role in early development and gene regulation, according to a new study published in Nature that challenges decades of biochemical assumptions. ...

A brief kidney crisis in childhood can cast a long shadow over health for years afterward

Acute kidney injury (AKI) is a condition in which the kidneys suddenly lose their ability to filter waste from the blood. Developing within hours or days, AKI can cause dangerous waste accumulation and disrupt the body's ...

Common asthma drug shows promise for reversing fatty liver

MUSC researchers are tackling MASH, or metabolic dysfunction-associated steatohepatitis, a liver disease affecting hundreds of millions worldwide. It is also a leading cause of liver transplantation, yet treatment options ...

Longer dialysis times associated with better survival

For adults undergoing maintenance in-center hemodialysis, longer dialysis times are associated with better survival, according to a study published in the June issue of Kidney International Reports.

Contrast agents in imaging—do they really harm the kidneys?

"Contrast harms the kidneys"—this belief has been present among patients for years, and sometimes also among physicians. In clinical practice, it may raise concerns about imaging examinations and procedures that use contrast ...

Diabetes drug may protect against kidney inflammation

A new Northwestern Medicine study has shed light on how a class of diabetes drugs may protect the kidneys—not just by lowering blood sugar, but by triggering a molecular shift that dampens inflammation, according to a study ...

Obesity genes tied to kidney, eye and nerve damage in diabetes

A large genome-wide analysis reports that common obesity traits share, and in some cases drive, risk for diabetic kidney disease, diabetic retinopathy, and diabetic neuropathy. The study maps shared DNA signals, tests causal ...

Protein in urine can predict risk of dementia

A new study shows that people with higher levels of the protein albumin in their urine are at increased risk of developing dementia. The study, led by researchers at Karolinska Institutet, is published in the Journal of Internal ...

New pill lowers stubborn BP in kidney patients

A novel pill that blocks the hormone aldosterone shows promise for lowering blood pressure and potentially delaying the progression of kidney disease in people with both conditions.