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Nephrology news

Turning up protein production: A new genetic approach to polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney failure. Despite decades of research, treatment options for the disease remain limited, and many patients ultimately require ...

A painless punch with a microneedle patch could detect kidney disease earlier

Kidney disease is silent in its early stages, progressing without symptoms until the disease is advanced. Researchers in the McKelvey School of Engineering at Washington University in St. Louis, in collaboration with researchers ...

Genetic variants shed light on kidney transplant rejection

Immunosuppressive medications help prevent organ rejection following transplantation, yet some patients still experience rejection despite receiving adequate treatment. New research from Yale, published in the Journal of ...

Renal impairment linked to age-related macular degeneration

Renal impairment and age-related macular degeneration (AMD) are interrelated, with higher odds of AMD among individuals with chronic kidney disease (CKD), according to a review published in the American Journal of Ophthalmology.

Kidney disease is also a brain disease. Here's why

When we think of kidney disease, we think of dialysis or a kidney transplant. Less well known is that kidney disease, which affects more than 10% of the world's population, can have significant consequences for the functioning ...

Hemodialysis mortality risks by blood type

Do you know your blood type? It is important information used for blood transfusions, but few realize that blood types could also be linked to disease risks. In the general population, people with blood type O have been reported ...

Possible therapeutic targets for kidney disease identified

Chronic kidney disease (CKD) is on the rise in the United States, with roughly 36 million adults estimated to have the condition. As more people develop the disease, researchers from the University of Missouri School of Medicine ...

Stem cell vesicles show promise for treating kidney injury

Researchers from the Germans Trias i Pujol Research Institute (IGTP) have published a review analyzing the therapeutic potential of extracellular vesicles derived from mesenchymal stem cells to address kidney injury. The ...

A 'magic bullet' for polycystic kidney disease in the making

Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the painful, growing cysts rob the organs of their function, often leading ...

New tool predicts graft failure after kidney transplant

Researchers at The Johns Hopkins Medicine say they have developed a new electronic medical records-based tool that should help doctors predict which patients are most at risk of losing a transplanted kidney graft.

Congenital heart disease mutation linked to kidney damage

Biomedical engineers at Duke University have shown that a genetic mutation that causes congenital heart disease also contributes to kidney damage and developmental defects. Identifying this early cause of kidney damage could ...