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Nephrology news

'Toxic' molecule may play vital role in gene regulation and development

A molecule once thought to be a harmful metabolic byproduct may play a crucial role in early development and gene regulation, according to a new study published in Nature that challenges decades of biochemical assumptions. ...

A brief kidney crisis in childhood can cast a long shadow over health for years afterward

Acute kidney injury (AKI) is a condition in which the kidneys suddenly lose their ability to filter waste from the blood. Developing within hours or days, AKI can cause dangerous waste accumulation and disrupt the body's ...

Common asthma drug shows promise for reversing fatty liver

MUSC researchers are tackling MASH, or metabolic dysfunction-associated steatohepatitis, a liver disease affecting hundreds of millions worldwide. It is also a leading cause of liver transplantation, yet treatment options ...

Longer dialysis times associated with better survival

For adults undergoing maintenance in-center hemodialysis, longer dialysis times are associated with better survival, according to a study published in the June issue of Kidney International Reports.

Contrast agents in imaging—do they really harm the kidneys?

"Contrast harms the kidneys"—this belief has been present among patients for years, and sometimes also among physicians. In clinical practice, it may raise concerns about imaging examinations and procedures that use contrast ...

Kidney fibrosis linked to molecule made by gut bacteria

A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis—a serious complication of diabetes and a leading cause of kidney failure—according ...

How mutations in bodily tissues affect aging

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature Aging, show that such mutations ...

High metabolic syndrome severity linked to development of CKD

High metabolic syndrome (MetS) severity, expressed by the continuous metabolic syndrome severity score (cMetS-S), is associated with development of chronic kidney disease (CKD), according to a study recently published in ...

Dietary patterns linked to chronic kidney disease risk

Compared with other dietary indices, Dietary Approaches to Stop Hypertension (DASH) and the Dietary Inflammatory Index (DII) provide chronic kidney disease (CKD) risk discrimination, according to a study published online ...

Lupus low disease activity state attainable in lupus nephritis

In lupus nephritis, attainment of complete renal response (CRR)/partial renal response (PRR) and lupus low disease activity state (LLDAS) is associated with best relapse-free survival, with independent associations seen with ...