Mathematical model unlocks key to brain wiring

(Medical Xpress) -- A new mathematical model predicting how nerve fibres make connections during brain development could aid understanding of how some cognitive disorders occur.

The model, constructed by scientists at the Queensland Institute (QBI) and School of Mathematics and Physics at the University of Queensland (UQ), gives new insight into how changing chemical levels in fibres can modify nerve wiring underpinning connections in the brain.

Professor Geoff Goodhill says that while scientists have long known that changing these chemical levels can change where nerve fibres grow, only now are they understanding why this is the case.

“Our allows us to predict precisely how these chemical levels control the direction in which nerve fibres grow, during both neural development and regeneration after injury,” he said.

Correct brain wiring is fundamental for normal brain function.

Recent discoveries suggest that wiring problems may underpin a number of nervous system disorders including autism, dyslexia, Down syndrome, Tourette's syndrome and Parkinson's disease.

The new model, published in the prestigious cell journal Neuron demonstrates the important role mathematics can play in understanding how the brain develops, and perhaps ultimately preventing such disorders.

Citation: Mathematical model unlocks key to brain wiring (2012, May 10) retrieved 16 July 2019 from https://medicalxpress.com/news/2012-05-mathematical-key-brain-wiring.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more