Rapidly progressive alopecia shows favorable prognosis

October 9, 2012
Rapidly progressive alopecia shows favorable prognosis
Patients with rapidly progressive alopecia areata tend to show favorable prognosis regardless of treatment selected, according to research published online Sept. 24 in the Journal of the American Academy of Dermatology.

(HealthDay)—Patients with rapidly progressive alopecia areata (RPAA) tend to show favorable prognosis regardless of treatment selected, according to research published online Sept. 24 in the Journal of the American Academy of Dermatology.

Over a three-year period, Masaki Uchiyama, M.D., from the Tokyo Medical University, and colleagues retrospectively analyzed 1,030 patients diagnosed with AA.

The researchers found that patients with regenerated vellus hairs showed a significantly higher improvement or cure rate regardless of AA severity. Lower rates of cure and higher rates of relapse were significantly associated with early onset and lengthy duration. Regardless of treatment utilized, RPAA patients tended to show a good prognosis.

"Our study suggested that there was no statistically significant influence of the initial treatment modalities on the prognosis of AA patients with , including both RPAA and chronic persistent AA," Uchiyama and colleagues conclude. "Recent studies have demonstrated that AA is associated with autoimmunity. However, RPAA patients tend to have a favorable prognosis, and the of curable RPAA is thought to be less associated with the autoimmune system than chronic forms of AA."

Explore further: Adolescents can benefit from 12-step involvement

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Adolescents can benefit from 12-step involvement

April 16, 2012
Adolescents who misuse alcohol and other drugs to the point where they need treatment must contend with costly and limited options for youth-specific care, as well as high relapse rates following treatment. Mutual-help groups ...

Recommended for you

Creation of synthetic horsepox virus could lead to more effective smallpox vaccine

January 19, 2018
UAlberta researchers created a new synthetic virus that could lead to the development of a more effective vaccine against smallpox. The discovery demonstrates how techniques based on the use of synthetic DNA can be used to ...

Study ends debate over role of steroids in treating septic shock

January 19, 2018
The results from the largest ever study of septic shock could improve treatment for critically ill patients and save health systems worldwide hundreds of millions of dollars each year.

New approach could help curtail hospitalizations due to influenza infection

January 18, 2018
More than 700,000 Americans were hospitalized due to illnesses associated with the seasonal flu during the 2014-15 flu season, according to federal estimates. A radical new approach to vaccine development at UCLA may help ...

Zika virus damages placenta, which may explain malformed babies

January 18, 2018
Though the Zika virus is widely known for a recent outbreak that caused children to be born with microencephaly, or having a small head, and other malformations, scientists have struggled to explain how the virus affects ...

Certain flu virus mutations may compensate for fitness costs of other mutations

January 18, 2018
Seasonal flu viruses continually undergo mutations that help them evade the human immune system, but some of these mutations can reduce a virus's potency. According to new research published in PLOS Pathogens, certain mutations ...

Study reveals how MRSA infection compromises lymphatic function

January 17, 2018
Infections of the skin or other soft tissues with the hard-to-treat MRSA (methicillin-resistant Staphylococcus aureus) bacteria appear to permanently compromise the lymphatic system, which is crucial to immune system function. ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.