Study finds dramatic increase in hospitalization of US children with inflammatory bowel disease

June 25, 2013

The largest investigation to date has found a dramatic increase in the number of hospitalizations for children with inflammatory bowel disease (IBD) during the past decade in the United States.

The new study, published online and scheduled for the August 2013 print issue of the Journal of Investigative Medicine, found a 65 percent increase in IBD from 2000 to 2009. The number increased from 11,928 discharges in 2000 to 19,568 discharges in 2009.

IBD refers to a group of of the colon and . The major types of IBD are Crohn's disease (CD) and (UC). When looking at these two types of IBD individually, the authors found a 59 percent increase in CD discharges and a 71 percent increase UC discharges.

The study looked at more than 11 million hospitalization records of patients 20 years old and younger using a federal children's inpatient database. For the decade, they identified more than 61,000 pediatric discharges with an IBD diagnosis.

According to the study's principal investigator, Thomas J. Sferra, MD, Division Chief of Pediatric Gastroenterology and Nutrition at UH & Children's Hospital and Associate Professor of Pediatrics at Case Western Reserve University School of Medicine, this increasing trend was present in each age category and across all geographic regions (Northeast, Midwest, South and West).

"The reason for this large increase in hospitalizations of children with IBD is not clear," said Dr. Sferra. "We also found an increase in IBD-related complications and co-existing conditions which suggest an increase in the severity of this disease has contributed to a greater need for hospitalization. However, we will need to perform more research to determine whether patients were admitted to the hospital due to IBD or for an unrelated medical condition. Also, while we're seeing more kids being discharged with IBD, we cannot with certainty say that the incidence and prevalence of childhood IBD has increased in U.S."

The trend found by this nationwide study reflects what appears to be a phenomenon that has been reported for specific regions within the US and for other countries—Canada, Scotland, and Finland.

Explore further: Inflammatory bowel disease raises risk of melanoma

More information: journals.lww.com/jinvestigativ … dren_With.99687.aspx

Related Stories

Inflammatory bowel disease raises risk of melanoma

May 20, 2013
Patients with inflammatory bowel disease (IBD) are at higher risk of melanoma, a form of skin cancer, report researchers at Mayo Clinic. Researchers found that IBD is associated with a 37 percent greater risk for the disease. ...

Flu vaccine safe for children with IBD, study shows

May 6, 2013
Influenza immunization rates in children with inflammatory bowel disease (IBD) are low despite its safety according to a new study by researchers at the Institute for Clinical Evaluative Sciences (ICES), Children's Hospital ...

Biomarkers discovered for inflammatory bowel disease

May 21, 2013
Using the Department of Defense Serum Repository (DoDSR), University of Cincinnati (UC) researchers have identified a number of biomarkers for inflammatory bowel disease (IBD), which could help with earlier diagnosis and ...

Females fend off gut diseases

June 11, 2013
At least among mice, females have innate protection from certain digestive conditions, according to a new Michigan State University study.

Advances in inflammatory bowel disease—what's new, what's next

March 22, 2013
Every five years, the Crohn's & Colitis Foundation of America (CCFA) gathers top researchers in inflammatory bowel disease (IBD) to set the research agenda for the next five years. The findings and recommendations of these ...

Recommended for you

New compound discovered in fight against inflammatory disease

September 22, 2017
A 10-year study by University of Manchester scientists for a new chemical compound that is able to block a key component in inflammatory illness has ended in success.

Asthma researchers test substance from coralberry leaves

September 14, 2017
The coralberry could offer new hope for asthmatics. Researchers at the University of Bonn have extracted an active pharmaceutical ingredient from its leaves to combat asthma, a widespread respiratory disease. In mice, it ...

Respiratory experts urge rethink of 'outdated' asthma categorisation

September 12, 2017
A group of respiratory medicine experts have called for an overhaul of how asthma and other airways diseases are categorised and treated.

New 'biologic' drug may help severe asthma

September 7, 2017
(HealthDay)—A "biologic" drug in development to treat severe asthma reduces the rate of serious attacks by about two-thirds compared to a placebo drug, according to preliminary research findings.

Songbird study shows how estrogen may stop infection-induced brain inflammation

August 31, 2017
The chemical best-known as a female reproductive hormone—estrogen—could help fight off neurodegenerative conditions and diseases in the future. Now, new research by American University neuroscience Professor Colin Saldanha ...

New insights into protein's role in inflammatory response

July 28, 2017
A protein called POP2 inhibits a key inflammatory pathway, calming the body's inflammatory response before it can become destructive, Northwestern Medicine scientists have demonstrated in mouse models.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.