Impaired sleep ups risk of relapse in Crohn's disease

August 8, 2013
Impaired sleep ups risk of relapse in crohn's disease
For patients with Crohn's disease, but not ulcerative colitis, sleep impairment is associated with increased risk of relapse, according to a study published in the August issue Clinical Gastroenterology and Hepatology.

(HealthDay)—For patients with Crohn's disease (CD), but not ulcerative colitis, sleep impairment is associated with increased risk of relapse, according to a study published in the August issue Clinical Gastroenterology and Hepatology.

In an effort to examine the role of sleep disturbance on the risk of relapse, Ashwin N. Ananthakrishnan, M.D., M.P.H., from Massachusetts General Hospital in Boston, and colleagues analyzed data from 3,173 patients with (IBD; 1,798 in clinical remission at baseline) participating in a longitudinal, Internet-based cohort.

The researchers found that correlates of sleep disturbance at enrollment included disease activity, depression, female gender, smoking, and use of corticosteroids or narcotics. Of the 1,291 patients whose CD was in remission at baseline, the risk of active disease at six months was increased two-fold for those with impaired sleep (adjusted odds ratio, 2.00). This association was not seen for patients with ulcerative colitis. The results were consistent in different sensitivity analyses.

"In conclusion, we identified sleep impairment during remission to be a risk factor for disease flares in CD in a large IBD cohort," the authors write. "There is a need for further research on the potential benefits of routine assessment of sleep quality as well as intervention-based studies to improve sleep quality in patients with CD, which ultimately may impact ."

Explore further: Depressive symptoms tied to doubled risk for Crohn's

More information: Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Related Stories

Depressive symptoms tied to doubled risk for Crohn's

January 16, 2013
(HealthDay)—Depressive symptoms are associated with a two-fold increase in risk of Crohn's disease (CD) but not ulcerative colitis (UC), according to research published in the January issue of Clinical Gastroenterology ...

Ulcerative colitis, not crohn's, deaths down from 1982

January 21, 2013
(HealthDay)—Over the past 30 years in Denmark, mortality from ulcerative colitis (UC) has decreased, but mortality from Crohn's disease (CD) has remained persistently higher than the general population, according to research ...

Inflammatory bowel disease raises risk of melanoma

May 20, 2013
Patients with inflammatory bowel disease (IBD) are at higher risk of melanoma, a form of skin cancer, report researchers at Mayo Clinic. Researchers found that IBD is associated with a 37 percent greater risk for the disease. ...

Study finds dramatic increase in hospitalization of US children with inflammatory bowel disease

June 25, 2013
The largest investigation to date has found a dramatic increase in the number of hospitalizations for children with inflammatory bowel disease (IBD) during the past decade in the United States.

New research suggests glaucoma screenings for sleep apnea sufferers

August 7, 2013
August 7, 2013 – Researchers in Taiwan have discovered that people with sleep apnea are far more likely to develop glaucoma compared to those without the sleep condition. The results of this study, which is the first to ...

Sleep problems may increase risk for prostate cancer

May 7, 2013
Men who reported sleep problems, including difficulty falling asleep and staying asleep, had up to a twofold increased risk for prostate cancer, according to data published in Cancer Epidemiology, Biomarkers & Prevention, ...

Recommended for you

Fatty liver can cause damage to other organs via crosstalk

August 21, 2017
Nonalcoholic fatty liver disease is increasingly common. Approximately every third adult in industrialized countries has a morbidly fatty liver. This not only increases the risk of chronic liver diseases such as liver cirrhosis ...

Faulty gene linked to obesity in adults

August 18, 2017
Groundbreaking new research linking obesity and metabolic dysfunction to a problem in the energy generators in cells has been published by researchers from the Harry Perkins Institute of Medical Research and The University ...

Two lung diseases killed 3.6 million in 2015: study

August 17, 2017
The two most common chronic lung diseases claimed 3.6 million lives worldwide in 2015, according to a tally published Thursday in The Lancet Respiratory Medicine.

New test differentiates between Lyme disease, similar illness

August 16, 2017
Lyme disease is the most commonly reported vector-borne illness in the United States. But it can be confused with similar conditions, including Southern Tick-Associated Rash Illness. A team of researchers led by Colorado ...

Addressing superbug resistance with phage therapy

August 16, 2017
International research involving a Monash biologist shows that bacteriophage therapy – a process whereby bacterial viruses attack and destroy specific strains of bacteria - can be used successfully to treat systemic, multidrug ...

Can previous exposure to west Nile alter the course of Zika?

August 15, 2017
West Nile virus is no stranger to the U.S.-Mexico border; thousands of people in the region have contracted the mosquito-borne virus in the past. But could this previous exposure affect how intensely Zika sickens someone ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.