Research suggests that green tea, exercise boost weight loss, health

April 2, 2014 by A'ndrea Elyse Messer, Pennsylvania State University
Green tea. Credit: Wikimedia Commons

(Medical Xpress)—Mice on a high-fat diet that consumed decaffeinated green tea extract and exercised regularly experienced sharp reductions in final body weight and significant improvements in health, according to researchers in Penn State's College of Agricultural Sciences, who suggest that similar results could be realized by people.

After 16 weeks, high-fat-fed mice that exercised regularly and ingested green showed an average body mass reduction of 27.1 percent and an average abdominal fat mass reduction of 36.6 percent.

The mice on the green-tea-extract-and- regimen also experienced a 17 percent reduction in fasting blood glucose level, a 65 percent decrease in plasma insulin level and reduction in insulin resistance of 65 percent—all substantial improvements related to diabetic health.

Mice that ingested green tea extract but did not exercise or those that exercised but were not given green tea extract experienced less significant changes in weight and health measurements, noted lead researcher Joshua Lambert, associate professor of food science.

"What is significant about this research is that we report for the first time that voluntary exercise in combination with green tea extract reduced symptoms of metabolic syndrome and diet-induced obesity in high-fat-fed mice more significantly than either treatment alone," he said. "The changes in body weight and body fat may result from increased fat metabolism and decreased fat synthesis. Green tea seems to modulate genes related to energy metabolism."

Metabolic syndrome is the name for a group of risk factors—such as increased waist circumference, elevated triglycerides, reduced HDL-cholesterol, increased blood pressure and increased fasting blood glucose—that increase the chance of developing heart disease and other serious health problems, such as diabetes and stroke.

The research, which was published online in Molecular Nutrition Food Research in December 2013 and will appear in the April issue of the journal, indicates that people could realize similar benefits, Lambert pointed out.

"I think we can make that leap," he said. "When we put together our animal model experiments, we try to mimic the human situation as much as possible, so the dose of decaffeinated green tea that we used in this study is the equivalent of 8 to 10 cups of green tea a day, which is a lot for some people. But there are many people out there who are heavy, regular tea consumers."

Tea—Camellia sinensis—is rich in catechins, polyphenols that are natural antioxidents. A number of animal studies show the preventive effects of green tea polyphenols against obesity. A recent analysis of 11 human trials with green tea preparations reported a 1.31 kilogram average body weight loss in intervention groups compared to control groups.

Approximately 34 percent of adults in the United States are classified as obese. Obesity is a risk factor for metabolic syndrome. The most effective way to deal with the development of obesity and metabolic syndrome is lifestyle change, Lambert explained, adding that if people really want to lose weight, they need to exercise more to burn more calories, and they need to eat less.

"But our findings suggest that green tea in the absence of caffeine can enhance the effects of exercise," Lambert said. "The mice that exercised and had decaffeinated had a more significant change in body weight, and they had better outcomes as far as lower blood glucose and lower plasma insulin levels. It looks like a combination of exercise and decaffeinated green tea enhances the body's ability to use energy that is taken in."

Decaffeination may not be crucial to the study, Lambert noted, but he did not want the presence of caffeine in the tea to blur the results. Researchers focused on decaffeinated green tea because the literature shows that caffeine has a stimulatory effect. If mice or people ingest caffeine, it increases their basal metabolic rate and plays a role in increasing energy utilization and decreasing body weight.

Also, because a segment of the population remains skeptical of caffeine's effect on health and avoids it, Lambert eliminated it from the research.

The mice used in the research were preselected for their propensity to run. Like people, some mice aren't willing to run at all; others are willing to run constantly, Lambert said. Running wheels equipped with counters were placed in the cages and the mice ran voluntarily.

Although previous studies have shown that forced running or exhaustive swimming in combination with tea extract attenuate obesity in mice, there have been no previous reports on the effects of green tea in combination with voluntary exercise on obesity and in high-fat-fed mice. Forced exercise introduces other health problem into studies, Lambert said.

"Our rationale for looking at voluntary exercise as opposed to forced exercise is that people who are interested in reducing and dealing with diabetes and that sort of thing do have a high level of motivation," he said. "However, most people aren't in a situation where they are being forced to exercise. Supported or encouraged, yes, but forced, no."

Combining green-tea drinking and exercise may well help people—like mice—lose weight, but until research is done with humans, there is no way to be certain, Lambert stressed. "It looks promising for people, but somebody will have to do this experiment with people to definitively show that and exercise together have a beneficial effect in humans," he said.

The National Institutes of Health supported this work.

Explore further: Green tea helps mice keep off extra pounds

Related Stories

Green tea helps mice keep off extra pounds

October 4, 2011
Green tea may slow down weight gain and serve as another tool in the fight against obesity, according to Penn State food scientists.

Will green tea help you lose weight?

April 29, 2013
Evidence has shown that green tea extract may be an effective herbal remedy useful for weight control and helping to regulate glucose in type 2 diabetes. In order to ascertain whether green tea truly has this potential, Jae-Hyung ...

Drinking green tea with starchy food may help lower blood sugar spikes

November 9, 2012
An ingredient in green tea that helps reduce blood sugar spikes in mice may lead to new diet strategies for people, according to Penn State food scientists.

Green tea reduces cholesterol risk

July 8, 2011
(Medical Xpress) -- In a recent study published in the American Journal of Clinical Nutrition, Xin-Xin Zheng reports that green tea reduces LDL and total cholesterol. This could explain the reasoning behind green tea’s ...

Cocoa may help fight obesity-related inflammation

June 12, 2013
(Medical Xpress)—A few cups of hot cocoa may not only fight off the chill of a winter's day, but they could also help obese people better control inflammation-related diseases, such as diabetes, according to Penn State ...

Recommended for you

Who uses phone apps to track sleep habits? Mostly the healthy and wealthy in US

January 16, 2018
The profile of most Americans who use popular mobile phone apps that track sleep habits is that they are relatively affluent, claim to eat well, and say they are in good health, even if some of them tend to smoke.

Improvements in mortality rates are slowed by rise in obesity in the United States

January 15, 2018
With countless medical advances and efforts to curb smoking, one might expect that life expectancy in the United States would improve. Yet according to recent studies, there's been a reduction in the rate of improvement in ...

Teens likely to crave junk food after watching TV ads

January 15, 2018
Teenagers who watch more than three hours of commercial TV a day are more likely to eat hundreds of extra junk food snacks, according to a report by Cancer Research UK.

Can muesli help against arthritis?

January 15, 2018
It is well known that healthy eating increases a general sense of wellbeing. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have now discovered that a fibre-rich diet can have a positive influence ...

Your dishwasher is not as sterile as you think

January 13, 2018
(HealthDay)—Your dishwasher may get those plates spotless, but it is also probably teeming with bacteria and fungus, a new study suggests.

Study reveals what sleep talkers have to say

January 12, 2018
A team of researchers with members from several institutions in France has conducted a study regarding sleep talking and has found that most sleep talking is not only negative in nature, but involves a large amount of swearing. ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.