Cannabis extract can have dramatic effect on brain cancer, says new research

November 17, 2014 by Howard Wheeler
Cannabis extract can have dramatic effect on brain cancer, says new research

The new research by specialists at St George's, University of London, studied the treatment of brain cancer tumours in the laboratory and discovered that the most effective treatment was to combine active chemical components of the cannabis plant which are called cannabinoids.

Two of these called tetrahydrocannabinol (THC) and cannabidiol (CBD)were tested as part of the research into which is particularly difficult to treat and claims the lives of about 5,200 each year. It also has a particularly poor prognosis as the rate of survival after five years of patients' diagnosis is around 10%.

Cannabinoids are the active chemicals in and are also known more specifically as phytocannabinoids. There are 85 known cannabinoids in the cannabis plant.

The new research is the first to show a drastic effect when combining THC and CBD with . Tumours growing in the brains of mice were drastically slowed down when THC/CBD was used with irradiation.

Dr Wai Liu, Senior Research Fellow and lead researcher on the project, said: "The results are extremely exciting. The tumours were treated in a variety of ways, either with no treatment, the cannabinoids alone, and irradiation alone or with both the cannabinoids and irradiation at the same time.

"Those treated with both irradiation and the cannabinoids saw the most beneficial results and a drastic reduction in size. In some cases, the tumours effectively disappeared in the animals. This augurs well for further research in humans in the future. At the moment this is a mostly fatal disease.

"The benefits of the elements were known before but the drastic reduction of brain cancers if used with irradiation is something new and may well prove promising for patients who are in gravely serious situations with such cancers in the future."

The research team are discussing the possibility of combining with irradiation in a human clinical trial.

The research has been published in the Molecular Cancer Therapeutics journal.

Explore further: Study shows non-hallucinogenic cannabinoids are effective anti-cancer drugs

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21 comments

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Scottingham
4.4 / 5 (8) Nov 17, 2014
I know somebody who has a mostly inoperable brain tumor. He smokes weed like it was going out of style. It has been over 10 years since his diagnosis. I have little doubt that his smoking habits have let him live this long.
herbwarrior420
4.4 / 5 (7) Nov 17, 2014
There are many testimonials here in Colorado as well. Our government has known since 1974 that cannabis kills brain cancer (research 2 years UVA 72-74 suppose to find negatives of cannabis) couldn't kill mice and rats overdosing them with thc and it also killed and shrunk brain cancer tumors in mice and rats. With big pharm and industries lobbying (bribing) against cannabis and hemp (which isn't even a psychoactive drug and is schedule 1 drug) its full use and potential has only scratched the surface on the good thc and cbd's will help patients.
foolspoo
3.7 / 5 (3) Nov 17, 2014
continuing the trend of shedding ignorance through social media will only accelerate these inevitable changes Herb. change is a constant, of course, but spreading knowledge will help to ensure positivity in any changes.
Eddy Courant
4 / 5 (8) Nov 17, 2014
Nixon knew in '72. Then ordered the research sealed and created the DEA to keep it that way. What kind of president does this? What kind of human?
MP3Car
3.7 / 5 (3) Nov 18, 2014
Reminder (or informing those who do not know): U.S. Government, more specifically the Department of Health and Human Services (HHS), filed for a patent in 2001 on the usage of CBD to treat a variety of serious and uncurable illnesses, "The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia."

Marinol has been a prescription THC pill for at least a decade.

With these two facts, how is it that it remains DEA schedule I? If you say, "it's because when synthesized or isolated, it's no longer schedule I, but the raw plant remains schedule I." If that were true, then why are dried poppies and coca leaves schedule II? Schedule II has medicinal benefits, schedule I does not.

foolspoo
3.5 / 5 (4) Nov 18, 2014
Nixon knew in '72. Then ordered the research sealed and created the DEA to keep it that way. What kind of president does this? What kind of human?


a very very very average human. by every measure of the word average.
yep
3 / 5 (4) Nov 18, 2014
A president would do that to make his buddies and himself very wealthy.
http://www.academ...Business
Thorium Boy
2.5 / 5 (8) Nov 19, 2014
That potheads manage to inhibit the growth of anything related to the brain isn't a surprise. But, at least this seems like real medicinal use of THC, unlike the 80% in California who buy medical marijuana but use it recreationally, or re-sell it on the street for a profit.
yep
4.5 / 5 (8) Nov 19, 2014
That potheads manage to inhibit the growth of anything related to the brain isn't a surprise. unlike the 80% in California who buy medical marijuana but use it recreationally, or re-sell it on the street for a profit.

From your Handle it would seem you might have a clue, from your post it appears not. Before prohibition dating to antiquity all literature considered cannabis a mind stimulant and invigorator. It was government propaganda that turned it into "dope" to sway public opinion they used racism and disinformation to dissociate people from the most prescribed medicine on the planet and candy you could buy in the Sears and Roebuck catalog. The truth is any use is "medicinal", but it goes beyond that to the basic right of a free individual and their consciousness. The argument that Californians buy "medical marijuana" and re-sell it on the street is ludicrous because the black market is cheaper then the dispensaries. Educate yourself before you post more foolish drivel.
igorus
1.8 / 5 (5) Nov 19, 2014
So basically the tumor becomes like a stoner: to lazy to do anything and grow ;)
yep
4.2 / 5 (5) Nov 19, 2014
So basically the tumor becomes like a stoner: to lazy to do anything and grow ;)

Your Handle ought to be "ignoramus"
So another halfwit spreading the same propaganda. All mammals have endocannabanoid systems, why don't you look that up tool.
One of the many things cannabanoids do in our bodies is control atopsis, they shut done malfunctioning cells. It took over 30 years for us to figure that out because as Mussolini said "corporatism ought to be called fascism".
yep
4.2 / 5 (5) Nov 19, 2014
Sorry for being so harsh, I imagine your just trying to be cute, but this dismissive lazy dumb propaganda is used as justification to suppress the potential of humanity and control markets.
It needs to stop. Every petroleum based product on the market could be replaced by renewable biomass. The year it was prohibited 1937 popular mechanics did an article on Hemp as the billion dollar crop. Imagine the profits achieved by eliminating the only natural competition to as they said some fifty thousand industrial applications from fuel, paper, fiber, to medicine.
igorus
3 / 5 (1) Nov 20, 2014
@yep
Actually you can see the ;) smiley, making my comment a joke - not a good one but still.

Secondly I used to smoke for years and during the periods I smoked I was lazy, unproductive and my emotions were numb. Of course there are benefits of THC and cannabidol (like mentioned in this article), but let's not make it some kind of miracle drug, without any downsides.

I agree with you about the industrial application and I am pro-legalization, so we can control it and study more.
yep
5 / 5 (2) Nov 20, 2014
Yes, I was irritated by the same joke twice just worded slightly better especially because of the historical accounts before prohibition that I alluded to and maybe not you but some people are assholes and as you know sarcasm or jokes do not always go over well in print.
The effect is a personal choice that is why it is a convinient scapegoat. Do not blame the fork for making you fat or the gun for shooting someone.
Considering Dr Mechoulam in the eighties after 30 years of research said it would eliminate upwards of 30% of pharmaceuticals over night and be a major component in 50% of the remainder that classifies it as a miracle drug, munchies are not a always downside for those who get them especially chemo patients.
The nonsense needs to stop, people believe the lie that's why we are still here today.
yep
5 / 5 (1) Nov 20, 2014
Do not just take my word or a scientist that has spent a lifetime of reasearch, Google cannabis or "marijuana" patients eliminating pharmaceutical drugs and then tell me it's not a miracle.
antigoracle
4 / 5 (4) Nov 22, 2014
That's it, I'm moving to Colorado.
Protoplasmix
not rated yet Nov 22, 2014
Nixon knew in '72. Then ordered the research sealed and created the DEA to keep it that way. What kind of president does this? What kind of human?

High time we force bought-and-paid-for politicians into poverty and prisons by making them pee in a cup, or offer them deportation to any fascist country that would welcome them and their primitive, science-free ideals.
alfie_null
5 / 5 (3) Nov 23, 2014
Too bad news like this can't be discussed dispassionately. Instead, it gets used as a springboard for fervent proponents of legalization.

I'd be interested to know more about what causes this effect. Can it be used in other situations? Can it be optimized? Does the treatment have other side effects?
Protoplasmix
5 / 5 (2) Nov 23, 2014
Too bad news like this can't be discussed dispassionately. Instead, it gets used as a springboard for fervent proponents of legalization

Indeed. Understand the consequences of having to endure 40+ years of tyrannical, unscientific, fear/warmongering propaganda when it comes to passion and compassion. Understand the consequences of perpetrating a war against your own citizenry without any law commensurate with the law that grants rights such as free exercise of religion and security in person, papers and effects, and equal protection of the laws, i.e. law enforcement lacks the constitutional authority of an amendment, like they had prohibiting alcohol. And understand that this article is hardly the first one highlighting beneficial properties—the springboard you mention is the result of a social pendulum packed with a great deal of inertia finally swinging back from a costly, futile and corrupt effort to keep it in place for decades.
Protoplasmix
5 / 5 (2) Nov 23, 2014
Late edit: Why we need to end the war on drugs <-- Ethan Nadelmann, TEDGlobal 2014
yep
not rated yet Nov 27, 2014
Alfie your just about as ignorant as Vievet maybe you ought to dispassionately educate yourself on the subject, maybe by reading every government study which I have and there are several. Here are the largest in chronological order dates are aprox. Start with the U.S. Army's Panama study around 1918 then go to La Guardias commission 1944 followed by Nixons, 1972 ya the one he suppressed then the California 1991 one and ask yourself since these studies are true why have we wasted the last hundred years spending billions and making our communities less safe? Then ask yourself why were you duped into believing the nonsense you do and why aren't you outraged as it effects us all on multiple levels whether you want to believe it or not.

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