High-value research of 2014 presented for hematology

May 8, 2015

High-value research of 2014 presented for hematology
(HealthDay)—Articles relating to malignant hematology, transfusion medicine, and bleeding and clotting disorders are included in a special update summary published online April 30 in the Annals of Internal Medicine.

Alice D. Ma, M.D., from the University of North Carolina at Chapel Hill, summarized studies relating to benign and malignant hematologic conditions published in 2014 that are relevant to practicing internists.

Ma highlighted the use of a new agent, idelalisib, which was added to rituximab to treat frail, elderly, pretreated patients with . A study that reported updated findings with personalized cellular therapeutics was also included for the treatment of relapsed in children and adults. Studies in the field of included one describing the superiority of a hemoglobin trigger of 70 g/L to a trigger of 90 g/L for determining when to transfuse blood to septic patients. An additional study examined the risk of hospital-acquired infections with red blood cell transfusions. Meta-analyses examined genomic-based strategies for warfarin dosing, and compared the best anticoagulant regimens for acute venous thromboembolism. A randomized trial found compression stockings to be ineffective for preventing post-thrombotic syndrome compared with sham compression hose.

"In addition to [these articles], it's also worth noting that in 2014, the American Society of Hematology published its second 'Choosing Wisely' list," Ma writes. "The Society has added five commonly used tests, treatments, and procedures in hematology that might not always be necessary."

Ma disclosed financial ties to the pharmaceutical and medical device industries.

Explore further: High-value research of 2014 presented for internal medicine

More information: Full Text (subscription or payment may be required)

Related Stories

High-value research of 2014 presented for internal medicine

May 4, 2015
(HealthDay)—Articles relating to atrial fibrillation, venous thromboembolism, acute bronchitis, ambulatory blood pressure monitoring for hypertension screening, and guidelines relevant to generalist practice are included ...

High-value research of 2014 presented for peri-op medicine

May 7, 2015
(HealthDay)—Articles relating to perioperative cardiac medicine, perioperative β-blocker use, perioperative pulmonary medicine, venous thromboembolism prophylaxis, and perioperative medication management are included in ...

High-value research of 2014 presented for geriatric medicine

May 5, 2015
(HealthDay)—Articles relating to overtreatment of cardiovascular disease, osteoporosis, and dementia care, as well as reduction of polypharmacy and adverse drug effects, are included in a special update summary published ...

High-value research of 2014 presented for endocrinology

May 4, 2015
(HealthDay)—Articles relating to diabetes and obesity, lipid management, bone metabolism, adrenal disorders, and thyroid disorders are included in a special endocrinology update summary published online April 30 in the ...

High-value research of 2014 presented for gastroenterology

May 6, 2015
(HealthDay)—Articles relating to esophageal diseases, pancreatic cancer, colorectal cancer, inflammatory bowel disease, liver disease, and other topics are included in a special gastroenterology and hepatology update summary ...

AABB releases new guidelines for red blood cell transfusion

March 26, 2012
AABB (formerly known as the American Association of Blood Banks) recommends a restrictive red blood cell transfusion strategy for stable adults and children, according to new guidelines being published in Annals of Internal ...

Recommended for you

Non-coding genetic variant could improve key vascular functions

November 15, 2018
Atherosclerotic disease, the slow and silent hardening and narrowing of the arteries, is a leading cause of mortality worldwide. It is responsible for more than 15 million deaths each year, including an estimated 610,000 ...

Study of two tribes sheds light on role of Western-influenced diet in blood pressure

November 14, 2018
A South American tribe living in near-total isolation with no Western dietary influences showed no increase in average blood pressure from age one to age 60, according to a study led by researchers at Johns Hopkins Bloomberg ...

Heart failure patients shouldn't stop meds even if condition improves: study

November 13, 2018
(HealthDay)—There's bad news for heart failure patients with dilated cardiomyopathy who'd like to stop taking their meds.

Bypass beats stents for diabetics with heart trouble: study

November 13, 2018
(HealthDay)—People with both diabetes and multiple clogged heart arteries live longer if they undergo bypass surgery rather than have their blood vessels reopened with stents, according to follow-up results from a landmark ...

Kawasaki disease: One disease, multiple triggers

November 12, 2018
Researchers at University of California San Diego School of Medicine, Scripps Institution of Oceanography, and international collaborators have evidence that Kawasaki Disease (KD) does not have a single cause. By studying ...

New treatment significantly reduces cardiovascular events when combined with statins

November 12, 2018
Statins are the most commonly used treatment for cardiovascular disease. Despite reducing certain risk factors, if triglyceride levels remain high with use of statins, there is still a significant risk for heart attack, stroke ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.