Online registry improves clinical research study participation

Research for Her, Cedars-Sinai's groundbreaking online registry that matches women with research studies and clinical trials, enrolled study participants more quickly when compared with traditional paper-based registries, according to new research published in the journal Gynecologic Oncology.

Historically, fewer women have participated in and only 3 to 5 percent of patients nationally enroll in trials.

"Research for Her is committed to changing these statistics and improving patient lives," said B.J. Rimel, MD, co-principal investigator of Research for Her, part of the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, and first author of the study.

A total of 322 women were enrolled in the Cedars-Sinai Research for Her registry over a 14-month period - a 4.3 fold increase over the paper-based registry. Of these 322 women, 263 were matched to at least one study and of those, 39 eligible individuals went on to enroll. The enrollment process increased in speed by 27 percent.

The Research for Her registry also spurred a 50 percent increase in enrollments for the Gilda Radner Hereditary Cancer Program, part of the Women's Cancer Program at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, in 2014. Founded in 1991, the Gilda Radner program consists of several research studies for women at higher risk for breast and ovarian cancer.

Research for Her, created in 2013, is currently open to all over the age of 18 with or without a prior history of cancer. It soon will expand to also enroll and link men to available or research studies at Cedars-Sinai.

"The early successes of Research for Her are encouraging," said Steven Piantadosi, MD, PhD, director of the Samuel Oschin Comprehensive Cancer Institute and the Phase One Foundation Chair. "We are eager to continue fostering the program's growth and potential, while bolstering patient lives."

Next steps also include identifying innovative methods to capture complex data from patients - such as molecular tumor profiling - to further decrease the time to enrollment for studies and provide more comprehensive prescreening for patients.

Explore further

Research for Her, an online clinical research registry, honored with distinguished national award

More information: Gynecologic Oncology: 2015 July: A novel clinical trial recruitment strategy for women's cancer.
Journal information: Gynecologic Oncology

Citation: Online registry improves clinical research study participation (2015, July 13) retrieved 17 August 2019 from
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