Possible miscarriage gene found: study

Recurrent spontaneous abortion is defined as a woman suffering three or more miscarriages within the first five weeks of pregnan
Recurrent spontaneous abortion is defined as a woman suffering three or more miscarriages within the first five weeks of pregnancy. It affects about one in every 100 pregnancies

Scientists said Wednesday they had linked mutations in a specific gene with an increased risk of recurrent miscarriages, offering hopes of better diagnosis and treatment for affected women.

The gene, dubbed FOXD1, was first pinpointed in , a team of international researchers wrote in the Royal Society Journal Open Biology.

They then investigated whether 556 women affected by "recurrent spontaneous abortion" or RSA, had mutations in the same gene. They did.

RSA is defined as a woman suffering three or more miscarriages within the first five weeks of pregnancy. It affects about one in every 100 pregnancies.

A control group of 271 non-RSA sufferers were also included in the study.

"We found that women with FOXD1 mutations have a statistically high risk of suffering RSA," said the team.

They also found one variant present only in the of with no history of miscarriage, and speculated it may be protective.

It is not the first gene implicated in repeated miscarriage, though "functional evidence" of their involvement has been rare, the team wrote.


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More information: Association of FOXD1 variants with adverse pregnancy outcomes in mice and humans, Open Biology, rsob.royalsocietypublishing.or … /10.1098/rsob.160109
Journal information: Open Biology

© 2016 AFP

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Oct 19, 2016
There are already too many people in this world, this world is already burning. Helping women with recurrent spontaneous abortions would be like adding fuel to the fire. A nice graph showing the population: https://upload.wi...2000.png

By 2050, we won't have enough food worldwide because of overpopulation and global warming. We must already eat genetically modified foods. But gene manipulation also has its limitations. What's next? "Soylentes Green"? It would be really stupid helping women to get more children.

Some countries in Asia and Africa have already recognized this overpopulation problem. They have been trying to solve this problem with financial incentives, laws and (everyone reading this medical artice will be shocked?) mass abortions! Unfortunately mostly without significant success.

We should really try to solve this problem. Otherwise the lack of food will lead to crises and wars. I am ready to help.

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