Occipital nerve stimulation effective for chronic migraine

October 29, 2016

(HealthDay)—For patients with chronic migraine (CM), peripheral nerve stimulation of the occipital nerves reduces the number of headache days, according to a study published online Oct. 25 in Pain Practice.

Nagy A. Mekhail, M.D., Ph.D., from the Cleveland Clinic, and colleagues implanted 20 at a single center with a neurostimulation system, and randomized them to an active or control group for 12 weeks. Patients received open-label treatment for an additional 40 weeks.

The researchers observed a reduction in the number of headache days per month (8.51 days; P < 0.0001). Sixty and 35 percent of patients achieved a 30 and 50 percent reduction, respectively, in headache days and/or . All patients had reductions in Migraine Disability Assessment and Zung Pain and Distress scores. At least one adverse event was reported by 15 of the patients, with a total of 20 adverse events reported.

"Our results support the 12-month efficacy of 20 CM patients receiving peripheral nerve stimulation of the occipital nerves in this single-center trial," the authors write.

Explore further: Peripheral nerve blocks OK for migraines in pregnancy

More information: Full Text (subscription or payment may be required)

Related Stories

Peripheral nerve blocks OK for migraines in pregnancy

November 14, 2014
(HealthDay)—For migraines that do not respond to medications, peripheral nerve blocks may be a treatment option in pregnant women, according to research published online Nov. 5 in Obstetrics & Gynecology.

Radiofrequency neurotomy efficient in knee osteoarthritis

August 23, 2016
(HealthDay)—For patients with chronic knee osteoarthritis (OA) pain, radiofrequency (RF) neurotomy of genicular nerves is safe and efficient, according to a study published online Aug. 12 in the International Journal of ...

Migraine headache therapy shifts treatment focus from the head to the neck

October 26, 2016
A researcher at Murdoch University has investigated a migraine headache therapy which shifts treatment focus from the head to the neck.

High-frequency spinal cord stimulation provides better results in chronic back and leg pain

October 28, 2016
For patients with severe, chronic back and leg pain, a new high-frequency spinal cord stimulation (SCS) technique provides superior clinical outcomes, compared to conventional low-frequency SCS, reports a clinical trial in ...

Platelet-rich plasma SIJ injection cuts low back pain

October 3, 2016
(HealthDay)—For patients with chronic low back pain, ultrasound-guided sacroiliac joint (SIJ) injection with platelet-rich plasma (PRP) is effective for reducing pain, according to a study published online Sept. 27 in Pain ...

Prevalence of migraine up in patients with cardiac syndrome X

April 26, 2016
(HealthDay)—The prevalence of migraine headache is elevated in patients with cardiac syndrome X (CSX) compared to patients with coronary artery disease or healthy controls, according to a research letter published in the ...

Recommended for you

First proof a synthesized antibiotic is capable of treating superbugs

March 23, 2018
A "game changing" new antibiotic which is capable of killing superbugs has been successfully synthesised and used to treat an infection for the first time—and could lead to the first new class of antibiotic drug in 30 years.

Scientists identify potential drug target in blood-feeding hookworms

March 22, 2018
In hookworms that infect and feed on the blood of mice, scientists have discovered a key step in blood digestion that can be targeted to disrupt the parasite's development and survival. These findings, published in PLOS Pathogens ...

Global burden of low back pain—a consequence of negligence and misinformation

March 21, 2018
A series of groundbreaking papers from Australian and international researchers in The Lancet, published today (22/3) warns that low back pain is a major health burden globally - across developed and developing nations - ...

Microscopic 'shuttles' transport enzyme from cells to trigger onset of kidney disease

March 21, 2018
A new study involving the University of Sheffield has identified a key culprit in the onset of kidney disease in a major marker for kidney disease development.

Metabolite therapy proves effective in treating C. difficile in mice

March 20, 2018
A team of UCLA researchers found that a metabolite therapy was effective in mice for treating a serious infection of the colon known as Clostridium difficile infection, or C. difficile.

Study of COPD patients has created a 'looking glass' into genome of pathogen

March 19, 2018
Decades of work on chronic obstructive pulmonary disease (COPD) at the University at Buffalo and the Veterans Affairs Western New York Healthcare System have yielded extraordinary information about the pathogen that does ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.