Hydrotherapy plus conventional drugs beneficial in RA

June 20, 2017

(HealthDay)—For patients with rheumatoid arthritis (RA), hydrotherapy in addition to conventional drugs is associated with improved antioxidant status, according to a study published online June 14 in the International Journal of Rheumatic Diseases.

Somaiya Mateen, from Jawaharlal Nehru Medical College in Aligarh, India, and colleagues enrolled 40 patients with RA and 30 age- and sex-matched healthy controls to examine the impact of hydrotherapy on oxidant-antioxidant status in RA. The authors subdivided the patients with RA into two groups to receive treatment with either conventional RA medications (20 patients) or hydrotherapy together with conventional drugs (20 patients) for 12 weeks.

The researchers found that patients with RA treated with hydrotherapy had a significant decrease in the Disease Activity Score of 28 joints, which was not seen after conventional treatment. Patients with RA showed significant change in the oxidative stress biomarkers, including , ferric reducing antioxidant potential, malondialdehyde, protein carbonyl, and tail length; they also had significant decreases in the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) . No significant change in these parameters was seen with conventional drug treatment. Cotreatment of drugs with hydrotherapy resulted in reductions in protein, lipid, and DNA oxidation by increasing the activities of SOD and GPx.

"In addition to , RA should be advised to have hydrotherapy (moderate intensity exercise) in their treatment regimen," the authors write.

Explore further: Certain criteria may be better than others in RA assessment

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Certain criteria may be better than others in RA assessment

June 19, 2017
(HealthDay)—For patients with rheumatoid arthritis (RA), the performances of the Clinical Disease Activity Index (CDAI) and Simplified Disease Activity Index (SDAI) appear to be better than that of the Disease Assessment ...

New relapse prediction tool reduces cost of rheumatoid arthritis treatment

June 16, 2017
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR) 2017 have shown that the combined use of two measurements to accurately predict the risk of relapse in patients with rheumatoid ...

Antioxidant-pregabalin cuts pain in chronic calcific pancreatitis

March 14, 2016
(HealthDay)—For patients with chronic calcific pancreatitis (CCP), antioxidant-pregabalin combination is associated with significant pain reduction, according to a study published online March 6 in the Journal of Gastroenterology ...

Short-course tocilizumab may up hep B reactivation in RA

February 13, 2017
(HealthDay)—For patients with rheumatoid arthritis (RA), one to three doses of tocilizumab may increase the risk of hepatitis B virus (HBV) reactivation, according to a study published online Feb. 3 in the International ...

Oxidative stress tied to early-onset androgenetic alopecia

December 27, 2016
(HealthDay)—Younger patients with early-onset androgenetic alopecia (AGA) have increased oxidative stress, according to a study published online Dec. 16 in the Journal of Cosmetic Dermatology.

Recommended for you

How the brain plays a role in rheumatoid arthritis inflammation

June 18, 2018
In patients with chronic inflammatory conditions, such as rheumatoid arthritis, there has been limited understanding of how this inflammation affects the brain.

New 3-D imaging analysis technique could lead to improved arthritis treatment

June 18, 2018
An algorithm to monitor the joints of patients with arthritis, which could change the way that the severity of the condition is assessed, has been developed by a team of engineers, physicians and radiologists led by the University ...

Joint resolution: A link between Huntington's disease and rheumatoid arthritis

May 15, 2018
Using new analytic tools, researchers at University of California San Diego School of Medicine and the Icahn School of Medicine at Mount Sinai have decoded the epigenetic landscape for rheumatoid arthritis (RA), a common ...

Get off the golf cart if you have knee osteoarthritis

April 28, 2018
From presidents to retirees, more than 17 million people over the age of 50 golf regularly. Knee osteoarthritis, which causes swelling, pain and difficulty moving the joint, is one of the leading causes of disability in this ...

How environmental pollutants and genetics work together in rheumatoid arthritis

April 19, 2018
It has been known for more than three decades that individuals with a particular version of a gene—human leukocyte antigen (HLA)—have an increased risk for rheumatoid arthritis.

The bugs in your gut could make you weak in the knees

April 19, 2018
Bacteria in the gut, known as the gut microbiome, could be the culprit behind arthritis and joint pain that plagues people who are obese, according to a new study published today in JCI Insight.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.