Patient profile impacts QOL with radiation Tx in head, neck cancer

August 11, 2017

(HealthDay)—There are patient characteristics and clinical factors independently associated with physical and mental quality of life (QOL) in patients with head and neck cancer undergoing radiotherapy, according to a study published online Aug. 2 in Head & Neck.

Guro Lindviksmoen Astrup, from Oslo University Hospital in Norway, and colleagues evaluated 133 patients with head and . From the initiation of radiotherapy through six months of follow-up, patients rated physical and mental QOL using the Short Form-12 five times.

The researchers found that QOL deteriorated during radiotherapy and gradually improved after completion. There was a negative association between less and both physical and mental QOL. There were also negative associations between older age, more comorbidities, more psychological symptoms, and concomitant chemotherapy with physical QOL. There were positive associations for male sex, fewer physical symptoms, surgery before , and concomitant chemotherapy with mental QOL.

"Clinicians can use knowledge on time course and associated characteristics to identify and inform patients at higher risk for diminished QOL," the authors write.

Explore further: More side effects with CRT plus metformin in head, neck cancer

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

More side effects with CRT plus metformin in head, neck cancer

May 7, 2017
(HealthDay)—Patients with advanced head and neck cancer undergoing chemoradiotherapy (CRT) and receiving metformin experience more side effects than patients not on metformin, according to research published online April ...

Depression up in post-radiation head and neck cancer survivors

August 16, 2013
(HealthDay)—For post-radiotherapy survivors of head and neck cancer, depression is fairly common, but treatment is underutilized, according to research published online Aug. 15 in JAMA Otolaryngology-Head & Neck Surgery.

Reduced cancer-independent life expectancy in head, neck cancer

June 27, 2017
(HealthDay)—Patients with head and neck cancer have reduced life expectancy, independent of cancer, according to a study published online June 22 in Head & Neck.

Empowerment linked to HRQoL in teen, young adult CA survivors

July 17, 2017
(HealthDay)—For adolescent and young adult (AYA) cancer survivors, empowerment is independently associated with health-related quality of life (HRQoL), according to research published online July 11 in Cancer.

Researchers urge radiotherapy for all patients with bone mets

February 13, 2017
(HealthDay)—For patients with bone metastases, those responding to radiotherapy experience greater pain reduction and better quality of life (QOL) at day 10 after radiotherapy, according to a study published online Feb. ...

High-observation protocol cuts length of stay in head, neck CA

July 7, 2017
(HealthDay)—A high-observation protocol (HOP) appears to optimize clinical care for patients with head and neck cancer undergoing primary surgery, according to a study published online June 20 in Head & Neck.

Recommended for you

Researchers use a molecular Trojan horse to deliver chemotherapeutic drug to cancer cells

February 23, 2018
A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

An under-the-radar immune cell shows potential in fight against cancer

February 23, 2018
One of the rarest of immune cells, unknown to scientists a decade ago, might prove to be a potent weapon in stopping cancer from spreading in the body, according to new research from the University of British Columbia.

Lab-grown 'mini tumours' could personalise cancer treatment

February 23, 2018
Testing cancer drugs on miniature replicas of a patient's tumour could help doctors tailor treatment, according to new research.

Study tracks evolutionary transition to destructive cancer

February 23, 2018
Evolution describes how all living forms cope with challenges in their environment, as they struggle to persevere against formidable odds. Mutation and selective pressure—cornerstones of Darwin's theory—are the means ...

Putting black skin cancer to sleep—for good

February 22, 2018
An international research team has succeeded in stopping the growth of malignant melanoma by reactivating a protective mechanism that prevents tumor cells from dividing. The team used chemical agents to block the enzymes ...

Cancer risk associated with key epigenetic changes occurring through normal aging process

February 22, 2018
Some scientists have hypothesized that tumor-promoting changes in cells during cancer development—particularly an epigenetic change involving DNA methylation—arise from rogue cells escaping a natural cell deterioration ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.