Endometriosis increases risk of complications during pregnancy and delivery

September 13, 2017
Pregnancy
Pregnancy test. Credit: public domain

A new meta-analysis shows that pregnant women with endometriosis are at greater risk for a host of complications during pregnancy and at delivery, including preterm birth and cesarean section. The study was published in the journal Fertility and Sterility.

"It's important that women with a history of endometriosis, and obstetricians caring for them, are aware of this association between prior endometriosis and higher risks of miscarriage, preterm birth, , cesarean delivery and a baby small for ," Vincenzo Berghella, M.D., Professor of Gynecology and Director of Maternal Fetal Medicine in the Department of Obstetrics and Gynecology at the Sidney Kimmel Medical College at Thomas Jefferson University. "These pregnancies deserve closer monitoring for these complications."

Endometriosis affects about 11 percent of women in the United States, is often diagnosed in the early reproductive years and is associated with endometrial tissue that travels and lodges in other parts of the body. Some of the symptoms include dagger-like abdominal pain, infertility and painful intercourse.

"Endometriosis is known to alter a woman's physiology in a way that could interfere with a number of stages of pregnancy," says Berghella. "From causing inflammation at the endometrium, to resisting the action of progesterone during implantation and throughout the pregnancy, there are a number of ways that endometriosis may affect the normal course of pregnancy."

Twenty four studies were included in the analysis comprising over a million women. The results show that women had a higher risk of , miscarriage, cesarean delivery and placenta previa. The study also showed that endometriosis was associated with birth of infants who were small for their gestational age. There was no association, however, between and gestational hypertension or preeclampsia.

"Prior studies looking at this issue have reported conflicting results," says Berghella. "Studies like ours help clarify the findings by pooling the data from many studies to give the field a more conclusive answer to a debated research question. The collective data is stronger than any single study alone and often helps shape opinion in the field."

Explore further: Breastfeeding reduces risk of endometriosis diagnosis

More information: Fabrizio Zullo et al, Endometriosis and obstetrics complications: a systematic review and meta-analysis, Fertility and Sterility (2017). DOI: 10.1016/j.fertnstert.2017.07.019

Related Stories

Breastfeeding reduces risk of endometriosis diagnosis

August 30, 2017
Endometriosis is a chronic and incurable gynecologic disorder that affects approximately 10 percent of women in the United States. Its symptoms can be debilitating and include chronic pelvic pain, painful periods and pain ...

Endometriosis associated with a greater risk of complications in pregnancy

June 14, 2015
Women with endometriosis are at an increased risk of miscarriage and ectopic pregnancy, according to results of a huge nationwide study presented today. Moreover, women with a history of endometriosis whose pregnancies progressed ...

The benefits of exercise during pregnancy

July 7, 2016
Researchers collected and re-examined clinical trial data on exercise during pregnancy and whether it plays a role in preterm birth, and found that exercise is safe and does not increase the risk of preterm birth. In addition, ...

Infertility risk posed by endometriosis may be half of previous estimation

May 17, 2016
About 5 to 10 percent of the general female population is affected with endometriosis, and a higher prevalence is found among women with infertility. Although endometriosis is commonly observed in women who are infertile, ...

Weight gain greater, less than recommended during pregnancy linked with increased risk of adverse outcomes

June 6, 2017
In an analysis that included more than 1.3 million pregnancies, weight gain during pregnancy that was greater or less than guideline recommendations was associated with a higher risk of adverse outcomes for mothers and infants, ...

Overall favorable outcomes for twin pregnancies in moms 45-plus

April 11, 2017
(HealthDay)—Twin pregnancies in older women (at least 45 years of age) overall have favorable outcomes but are associated with high rates of some complications, according to a study published in the May issue of Obstetrics ...

Recommended for you

Sleeping position linked to the risk of stillbirth

November 20, 2017
Pregnant women who go to sleep on their back during the later stages of pregnancy face an increased likelihood of suffering a stillbirth, according to new research.

Study in mice finds dietary levels of genistein may adversely affect female fertility

November 14, 2017
Exposure to the phytoestrogen genistein prior to conception may adversely affect female fertility and pregnancy outcomes, depending on the dosage and duration of exposure, a new study in mice suggests.

IUDs may have a surprising benefit: Protection against cervical cancer

November 7, 2017
Considered a safe and highly effective contraception method, intrauterine devices (IUDs) may also be quietly offering protection against the third-most common cancer in women worldwide. A new study from the Keck School of ...

Increasing rates of chronic conditions putting more moms, babies at risk

November 7, 2017
Pregnant women today are more likely to have chronic conditions that could cause life-threatening complications than at any other time in the past decade - particularly poor women and those living in rural communities, a ...

First time mums with an epidural who lie down more likely to have a normal birth

October 18, 2017
Adopting a lying down position rather than being upright in the later stages of labour for first-time mothers who have had a low dose epidural leads to a higher chance of them delivering their baby without any medical intervention, ...

Mice delivered by C-section gain more weight than those delivered naturally

October 11, 2017
Mice born by Caesarian section gained on average 33 percent more weight in the 15 weeks after weaning than mice born vaginally, with females gaining 70 percent more weight.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.