Ibuprofen better choice over oral morphine for pain relief in children after minor surgery

October 10, 2017
Generic ibuprofen. Credit: Wikipedia

Widely available ibuprofen is a better choice for pain relief in children who have undergone minor orthopedic outpatient surgery, as it has fewer adverse effects compared with oral morphine, according to results from a clinical trial published in CMAJ (Canadian Medical Association Journal).

"This result suggests that adequate pain management should be an important goal of care, even after minor outpatient surgery, and that more effective pharmacologic and nonpharmacologic strategies should be explored," writes Dr. Naveen Poonai, Clinician Scientist, Lawson Health Research Institute, and Associate Professor, Emergency Medicine, Department of Paediatrics, Schulich School of Medicine & Dentistry, Western University, with coauthors.

The study included 154 children aged 5 to 17 years who underwent minor orthopedic surgery, such as keyhole surgery on joints, ligament and tendon repair, suture or hardware removal at London Health Sciences Centre in London, Ontario.

In the first 24 hours, more than 80% of the children in the study needed at home. Pain scores for children in both the oral morphine and ibuprofen groups were similar, but the children receiving oral morphine reported more , such as nausea, vomiting, drowsiness, dizziness and constipation.

"Morphine did not provide superior analgesia, but was associated with significantly more adverse effects, making ibuprofen a better analgesic option," write the authors.

They note that as neither treatment completely relieved pain, more research is needed into effective pain relief, especially for more severe .

Oral use at home has not been previously studied in who have had minor surgery nor has it been compared with ibuprofen.

Explore further: Ibuprofen better choice to relieve fracture pain in children than oral morphine

More information: Naveen Poonai et al. Oral morphine versus ibuprofen administered at home for postoperative orthopedic pain in children: a randomized controlled trial, Canadian Medical Association Journal (2017). DOI: 10.1503/cmaj.170017

Related Stories

Ibuprofen better choice to relieve fracture pain in children than oral morphine

October 27, 2014
Although Ibuprofen and oral morphine both provide effective pain relief for children with broken limbs, ibuprofen is the recommended choice because of adverse events associated with oral morphine, according to a randomized ...

Some benefit for curcuminoids in knee osteoarthritis

May 26, 2017
(HealthDay)—Curcuminoids seem beneficial for knee osteoarthritis (OA), although they are less effective for pain relief than ibuprofen, according to a review and meta-analysis published online May 4 in the International ...

Morphine following common childhood surgery may be life threatening

January 26, 2015
Treating post-operative pain with morphine can cause life-threatening respiratory problems in some children who have had their tonsils and/or adenoids removed, new research has found.

Morphine effects similar to placebo in rheumatoid arthritis

July 27, 2017
(HealthDay)—For patients with chronic fatigue syndrome (CFS)/fibromyalgia (FM) or rheumatoid arthritis (RA), morphine has anti-hyperalgesic effects comparable to placebo, according to a study published online July 19 in ...

Patient-controlled anesthesia non-inferior after C-section

March 16, 2016
(HealthDay)—Early patient-controlled oral analgesia is non-inferior to standard parenteral analgesia for pain management after elective cesarean section, according to a study published online March 2 in Anaesthesia.

Reducing stress, optimizing coping strategies may diminish need for opioids following ankle surgery

July 6, 2017
Helping patients to better manage stress and improve coping strategies related to pain may minimize the need for opioids following ankle fracture surgery, according to new research appearing in the July 2017 issue of the ...

Recommended for you

Defining optimal opioid pain medication prescription length following surgery

September 27, 2017
A new study led by researchers at the Center for Surgery and Public Health at Brigham and Women's Hospital analyzed opioid prescription data from the Department of Defense Military Health System Data Repository, identifying ...

Is older blood OK to use in a transfusion?

September 27, 2017
(HealthDay)—Using older red blood cells to give transfusions to critically ill patients doesn't appear to affect their risk of dying, Australian researchers report.

One weight-loss surgery shows lasting results

September 21, 2017
(HealthDay)—Obesity surgery can have long-lasting effects on weight and the risk of developing type 2 diabetes and high blood pressure, a new study finds.

Hold the phone: An ambulance might lower your chances of surviving some injuries

September 20, 2017
Victims of gunshots and stabbings are significantly less likely to die if they're taken to the trauma center by a private vehicle than ground emergency medical services (EMS), according to results of a new analysis.

Surgeons have major influence on breast cancer treatment

September 13, 2017
A woman's choice of surgeon plays a significant role in whether she's likely to receive an increasingly popular aggressive breast cancer surgery.

Some thyroid cancer patients can safely delay surgery

September 4, 2017
Most people diagnosed with cancer want to start treatment as soon as possible, for fear that delaying care will allow their tumor to grow out of control.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.