More patients with ulcerative colitis but fewer surgeries

October 17, 2017, Örebro Universitet
Carl Eriksson. Credit: Örebro Universitet

Today, a higher number of patients with ulcerative colitis are able to keep their bowel and steer clear of surgery, as shown in a study from Örebro University. Carl Eriksson, doctoral student at Örebro University, has also shown that the number of people suffering from the disease is 10 times higher today than in the 60s.

Carl Eriksson has examined the outcome for people developing the inflammatory bowel ulcerative colitis in Örebro between 1963 and 2010. Over 1,000 patients are part of the study.

More than 1 in 5 patients diagnosed before 1975 had to undergo surgery. This can be compared to 12 per cent of the patients developing the disease between 1991 and 2005.

"The risk of having to undergo surgery is clearly reduced now. I would like to think that this has to do with improved treatments," says Carl Eriksson.

Today, patients receive stronger treatments that reduce inflammation and symptoms. At the same , his study shows that the number of people developing the disease is significantly higher today than in the 60s.

"There are 10 times as many sufferers from ulcerative colitis today as in the 60s. Why there has been such an increase is an interesting question. One reason could be the fact that we do not smoke as much."

Research has shown that smoking protects against . Another reason, says Carl Eriksson, may be that healthcare has got better at identifying with inflammatory bowel conditions:

"More people are diagnosed since the examination methods are better today. But even if we account for that, there has been a significant increase," says Carl Eriksson.

Explore further: Asthma tied to later inflammatory bowel disease

More information: C. Eriksson et al. Changes in medical management and colectomy rates: a population-based cohort study on the epidemiology and natural history of ulcerative colitis in Örebro, Sweden, 1963-2010, Alimentary Pharmacology & Therapeutics (2017). DOI: 10.1111/apt.14268

Related Stories

Asthma tied to later inflammatory bowel disease

August 25, 2017
(HealthDay)—Asthma is associated with subsequent development of inflammatory bowel disease (IBD), according to a study published in the September issue of Clinical Gastroenterology and Hepatology.

Yoga helps patients with ulcerative colitis

April 5, 2017
Patients with ulcerative colitis, a chronic inflammatory bowel disease, often relapse at times of stress. In a clinical trial of 77 ulcerative colitis patients who were in clinical remission but were experiencing reduced ...

Inflammatory bowel disease in childhood associated with increased risk of cancer

September 21, 2017
Children who develop inflammatory bowel disease (ulcerative colitis or Crohn's disease) run a higher risk of cancer, both in childhood and later in life, a study from Karolinska Institutet published in the BMJ reports.

Fecal microbiota transplant is safe and effective for patients with ulcerative colitis

April 27, 2017
A single transplant of microbes contained in the stool of a healthy donor is a safe and effective way to increase diversity of good bacteria in the guts of patients with ulcerative colitis, according to new research from ...

Autoimmune diseases increase cardiovascular and mortality risk

August 30, 2017
Researchers from the Hospital del Mar Medical Research Institute (IMIM) and IDIAP Jordi Gol have just published an article showing that autoimmune diseases significantly increase cardiovascular risk as well as overall mortality. ...

Recommended for you

Largest oral HPV study in England shows infection rates lower than expected

August 20, 2018
Infection rates of high risk human papillomavirus (HR-HPV) oral infection in England are lower than expected, compared to previous US studies.

Tibetan sheep highly susceptible to human plague, originates from marmots

August 16, 2018
In the Qinghai-Tibet plateau, one of the region's highest risk areas for human plague, Himalayan marmots are the primary carriers of the infectious bacterium Y. pestis. Y. pestis infection can be transmitted to humans and ...

Autoimmunity plays role in development of COPD, study finds

August 16, 2018
Autoimmunity plays a role in the development of chronic obstructive pulmonary disease (COPD), according to a study led by Georgia State University and Vanderbilt University Medical Center that analyzed human genome information ...

Reliable point-of-care blood test can help prevent toxoplasmosis

August 16, 2018
A recent study, performed in Chicago and Rabat, Morocco, found that a novel finger-prick test for infection with the parasite Toxoplasma gondii during pregnancy—and many other potential applications—is 100 percent sensitive ...

Scientists identify nearly 200 potential tuberculosis drug targets

August 16, 2018
Tuberculosis is one of the top 10 causes of death worldwide. Nearly 2 million people die every year from this infectious disease, and an estimated 2 billion people are chronically infected. The only vaccine, developed almost ...

First mouse model to mimic lung disease could speed discovery of more effective treatments

August 16, 2018
The biggest hurdle to finding effective therapies for idiopathic pulmonary fibrosis (IPF) – a life-threatening condition in which the lungs become scarred and breathing is increasingly difficult – has been the inability ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.