Ovarian CA screening potentially cost-effective in the U.S.

Ovarian CA screening potentially cost-effective in the U.S.

(HealthDay)—Multimodal screening (MMS) for ovarian cancer is potentially cost-effective in the United States, according to a study published online Dec. 7 in JAMA Oncology.

In an effort to estimate the cost-effectiveness of MMS for in the United States, Haley A. Moss, M.D., from Duke University in Durham, N.C., and colleagues constructed a Markov simulation model to compare MMS beginning at age 50 years with no .

The researchers found that MMS is both more expensive and more effective in reducing ovarian cancer mortality over a lifetime, compared to no screening. MMS of women starting at age 50 years is cost-effective 70 percent of the time when decision makers are willing to pay $150,000 per quality-adjusted life-year, after accounting for uncertainty in the underlying parameters. There was a 15 percent reduction in mortality with screening, with an incremental cost-effectiveness ratio ranging from $106,187 to $155,256.

"These results are limited by uncertainty around the effect of screening on ovarian cancer mortality beyond the 11 years of [the] United Kingdom Collaborative Trial of Ovarian Cancer Screening," the authors write.

One author disclosed to the pharmaceutical industry.

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Journal information: JAMA Oncology

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Citation: Ovarian CA screening potentially cost-effective in the U.S. (2017, December 8) retrieved 7 July 2020 from https://medicalxpress.com/news/2017-12-ovarian-ca-screening-potentially-cost-effective.html
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