Weight loss among obese tied to improvements in chronic pain

January 29, 2018

(HealthDay)—For obese individuals with chronic pain, a weight loss intervention is associated with improvements in the spatial distribution of pain and comorbid somatic symptoms, according to a study published in the December issue of the Journal of Pain.

Andrew Schrepf, Ph.D., from the University of Michigan in Ann Arbor, and colleagues conducted an observational study to examine whether weight loss using a low-calorie diet improves pain, affect, and commonly associated with conditions. Participants were 123 obese individuals undergoing a 12- to 16-week weight loss intervention with calorie restriction. Before and after weight loss, the spatial distribution of pain, symptom severity, depression, and total fibromyalgia scale scores were measured.

The researchers found that after there were significant improvements in pain, symptom severity, depression, and fibromyalgia scores; greater improvement on somatic symptoms and fibromyalgia scores was seen for men versus women. Greater improvement was also seen for those who lost at least 10 percent of body weight compared with those who lost less than 10 percent. After the intervention, the levels of the regulatory cytokine interleukin-10 increased.

"Weight loss may improve diffuse pain and comorbid symptoms commonly seen in chronic pain participants," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Explore further: Patients use about half of opioids prescribed after hysterectomy

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Patients use about half of opioids prescribed after hysterectomy

November 10, 2017
(HealthDay)—Gynecologists prescribe about twice the amount of opioids than patients use after hysterectomy for benign, nonobstetric indications, according to a study published online Nov. 7 in Obstetrics & Gynecology.

Two simple tests can ID fibromyalgia in pain patients

November 1, 2017
(HealthDay)—Two simple tests can indicate a probable diagnosis of fibromyalgia (FM) in patients with chronic pain, according to a study published online Oct. 23 in the Journal of Evaluation in Clinical Practice.

Following bariatric surgery, use of opioids increases among chronic opioid users

October 1, 2013
In a group of patients who took chronic opioids for noncancer pain and who underwent bariatric surgery, there was greater chronic use of opioids after surgery compared with before, findings that suggest the need for proactive ...

Post-op pain may often be underrated by inpatient staff

July 20, 2017
(HealthDay)—Postoperative pain is frequently underrated when assessed by nursing staff on wards, according to a study published online July 14 in PAIN Practice.

Back pain in older men tied to incident vertebral fractures

September 26, 2017
(HealthDay)—Incident, clinically undiagnosed radiographic vertebral fractures (VFs) are associated with increased likelihood of back pain symptoms, according to a study published online Sept. 7 in the Journal of Bone and ...

Does widespread pain stem from the brain? MRI study investigates

August 10, 2017
Pain is the most common reason people seek medical care, according to the National Institutes of Health.

Recommended for you

Antibiotic prescribing influenced by team dynamics within hospitals

November 15, 2018
Antibiotic prescribing by doctors is influenced by team dynamics and cultures within hospitals.

Discovery suggests new route to fight infection, disease

November 14, 2018
New research reveals how a single protein interferes with the immune system when exposed to the bacterium that causes Legionnaires' disease, findings that could have broad implications for development of medicines to fight ...

Zika may hijack mother-fetus immunity route

November 14, 2018
To cross the placenta, Zika virus may hijack the route by which acquired immunity is transferred from mother to fetus, new research suggests.

Maternally acquired Zika immunity can increase dengue disease severity in mouse pups

November 14, 2018
To say that the immune system is complex is an understatement: an immune response protective in one context can turn deadly over time, as evidenced by numerous epidemiological studies on dengue infection, spanning multiple ...

New research aims to help improve uptake of hepatitis C testing

November 14, 2018
New research published in Scientific Reports shows persisting fears about HIV infection may impact testing uptake for the hepatitis C Virus (HCV).

Synthetic DNA-delivered antibodies protect against Ebola in preclinical studies

November 13, 2018
Scientists at The Wistar Institute and collaborators have successfully engineered novel DNA-encoded monoclonal antibodies (DMAbs) targeting Zaire Ebolavirus that were effective in preclinical models. Study results, published ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.