In pregnancy, buprenorphine use up, methadone use down

In pregnancy, buprenorphine use up, methadone use down

(HealthDay)—From 2009 to 2015, the prevalence of methadone use decreased and buprenorphine use increased among Medicaid-enrolled pregnant women with opioid use disorder, and the 4Ps Plus and Substance Use Risk Profile-Pregnancy (SURP-P) scale are sensitive for identifying illicit drug use, according to two studies published online April 5 in Obstetrics & Gynecology.

Elizabeth E. Krans, M.D., from the Magee-Womens Research Institute in Pittsburgh, and colleagues evaluated 12,587 pregnancies among 10,741 women with who had a between 2009 and 2015 to examine trends in medication-assisted treatment, opioid pharmacotherapy, and behavioral health counseling. The researchers observed a decrease in the adjusted prevalence of methadone use from 31.6 to 25.2 percent; the adjusted prevalence of buprenorphine use increased from 15.8 to 30.9 percent.

Victoria H. Coleman-Cowger, Ph.D., from the Batelle Memorial Institute in Baltimore, and colleagues compared and assessed the accuracy of three screening tools to identify and prescription drug misuse in pregnant women. A sample of 500 pregnant women were enrolled and administered three index tests—4Ps Plus, NIDA Quick Screen-ASSIST (Modified Alcohol, Smoking and Substance Involvement Screening Test), and the SURP-P scale—and reference tests. The researchers found that the sensitivity and specificity were 90.2 and 29.6 percent, respectively, for the 4Ps Plus; 79.7 and 82.8 percent, respectively, for the NIDA Quick Screen-ASSIST; and 92.4 and 21.8 percent, respectively, for the SURP-P.

"The dissemination of a strong and clear recommendation for a clinically useful prescription and illicit drug screening tool for is highly significant, relevant for , and will likely increase screening," Coleman-Cowger and colleagues write.

One author from the Krans study disclosed financial ties to the pharmaceutical industry.


Explore further

Prenatal food insecurity associated with severity of neonatal abstinence syndrome

More information: Abstract/Full Text (subscription or payment may be required) - Krans
Abstract/Full Text (subscription or payment may be required) - Coleman-Cowger
Journal information: Obstetrics & Gynecology

Copyright © 2019 HealthDay. All rights reserved.

Citation: In pregnancy, buprenorphine use up, methadone use down (2019, April 12) retrieved 16 October 2019 from https://medicalxpress.com/news/2019-04-pregnancy-buprenorphine-methadone.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
4 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more