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Video: How arsenic can help fight antibiotic resistance

Video: How arsenic can help fight antibiotic resistance
Patience Ngozi Paul. Credit: Florida International University

Most antibiotics on the market are becoming less effective. Arsenic may hold the answer to defeating resistant bacteria that have learned to fight back against the drugs designed to kill them.

Patience Ngozi Paul wants to understand how this therapeutic poison could be used to create the next generation of novel, more effective against deadly Mycobacteria, which cause tuberculosis.

Paul, a biomedical sciences Ph.D. candidate in the FIU Herbert Wertheim College of Medicine, is investigating arsinothricin (AST)—a new, broad-spectrum antibiotic containing arsenic discovered by Paul, and her advisors Distinguished University Professor Barry P. Rosen and assistant professor Masafumi Yoshinaga, along with a team of international researchers. Specifically, she's looking at how AST gets into . These cells have a membrane barrier preventing antibiotics from entering them. The goal is to ensure AST successfully gets into and destroys the bacteria cell.

Paul's research lays important groundwork and sets the stage for the development of drugs that can successfully overcome .

Can a deadly poison help fight a silent pandemic? Join Patience Paul as she delves into her groundbreaking research on how arsenic could solve one of humanity's greatest challenges—antibiotic resistance. Credit: Florida International University

Citation: Video: How arsenic can help fight antibiotic resistance (2023, June 6) retrieved 24 July 2024 from
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