After 20 years of trying, modern medicine remains unable to lower the roughly 40 percent mortality rate for the severe childhood immune disease called HLH (hemophagocytic lymphohistiocytosis), which damages vital organs and ...
May 7, 2020
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85
Researchers have found that environment has a much stronger role than genetics in eosinophilic esophagitis (EoE), a severe, often painful food allergy that renders children unable to eat a wide variety of foods.
Sep 22, 2014
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Imagine trying to paint a forest when all the artist has is a leaf and a piece of bark versus having a living, growing tree as a model. Seeing how the parts fit together can make all the difference.
Sep 25, 2019
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Researchers have successfully transplanted "organoids" of functioning human intestinal tissue grown from pluripotent stem cells in a lab dish into mice – creating an unprecedented model for studying diseases of the intestine.
Oct 19, 2014
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Teenagers with type 2 diabetes have significant changes in total brain gray matter volume and in regions of gray matter involved in seeing and hearing, memory, emotions, speech, decision making, and self-control.
Jun 14, 2016
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Nephrons are the microscopic blood-filtering units inside our kidneys that convert waste products into urine, regulate our electrolyte levels and our blood pressure.
May 21, 2018
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Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclinical laboratory tests.
Apr 10, 2018
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After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia (SCA) is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged ...
Dec 4, 2018
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Managing the activity of the BCAP protein could help the body repair intestinal tissue from damage caused by inflammation, according to a new study led by experts at Cincinnati Children's.
Nov 16, 2020
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New preclinical research shows a gene already linked to a subset of people with autism spectrum disorder is critical to healthy neuronal connections in the developing brain, and its loss can harm those connections to help ...
Jun 18, 2018
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