Scientists at the Gladstone Institutes linked a single gene mutation to two types of heart disease: one causes a hole in the heart of infants, and the other causes heart failure. Using cells donated by a family with the mutation, ...
Dec 15, 2016
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47
Scientists at the Gladstone Institutes have discovered how the major genetic risk factor for Alzheimer's disease causes memory impairment. A specific type of brain activity important for memory replay is disrupted in mice ...
May 6, 2016
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107
In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals. All previous work on cellular reprogramming required adding external ...
Apr 28, 2016
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309
Scientists at the Gladstone Institutes have invented a new way to create three-dimensional human heart tissue from stem cells. The tissue can be used to model disease and test drugs, and it opens the door for a precision ...
Apr 20, 2016
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56
Scientists at the Gladstone Institutes have invented a new way to read and interpret the human genome. The computational method, called TargetFinder, can predict where non-coding DNA—the DNA that does not code for proteins—interacts ...
Apr 4, 2016
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135
Scientists have long known that the protein tau is involved in dementia, but how it hinders cognitive function has remained uncertain. In a study published in the journal Neuron, researchers at the Gladstone Institutes reveal ...
Mar 31, 2016
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107
Clinical scientists at the University of California, San Francisco (UCSF) Memory and Aging Center have teamed up with preclinical researchers at the Gladstone Institutes to advance Alzheimer's disease research by developing ...
Jan 19, 2016
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28
Scientists at the Gladstone Institutes have discovered an unusual regulator of body weight and the metabolic syndrome: a molecular mechanism more commonly associated with brain cells. Lowering levels of P75 neurotrophin receptor ...
Jan 12, 2016
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190
Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF) have successfully converted human skin cells into fully-functional pancreatic cells. The new cells produced insulin in response ...
Jan 6, 2016
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844
Researchers from the Gladstone Institutes have shown for the first time that the protein BRCA1 is required for normal learning and memory and is depleted by Alzheimer's disease.
Nov 30, 2015
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315
