Gladstone Institutes

The Gladstone Institutes is comprised of three institutes in the San Francisco area which began in 1979. The Gladstone Institute of Cardiovascular Disease focuses on atherosclerosis and its complications. The Gladstone Institute of Virology and Immunology focuses on the origins of HIV/AID and development of treatment and prevention. The Gladstone Institute of Neurological Disease focuses on Alzheimer's Disease and related aging factors. The Gladstone Institute is an independent center for research, however it is affiliated with the University of California, San Francisco. The Gladstone Institutes have entered into joint research ventures with Merck & Co. Inc to form the Center for Translational Research. The center's focus is to bring about rapid drug discoveries and to bridge the gap between traditional basic research and making available therapies to treat patient diseases.

Address
1650 Owens Street San Francisco, CA 94158-2261
Website
http://www.gladstone.ucsf.edu/gladstone/site/gweb1/

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Medical research

Scientists transform skin cells into functioning liver cells

The power of regenerative medicine now allows scientists to transform skin cells into cells that closely resemble heart cells, pancreas cells and even neurons. However, a method to generate cells that are fully mature—a ...

Genetics

New genomic atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in ...

HIV & AIDS

Scientists identify a new potential reservoir of latent HIV

Scientists have long known that even in the face of antiretroviral therapy, some HIV virus remains in infected individuals forever, hiding in small reservoirs of cells of the immune system. When these individuals discontinue ...

Immunology

Toxic cell atlas guides new therapies for neurodegeneration

A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen ...

Neuroscience

Could targeting an Alzheimer's-associated protein prevent autism?

Autism manifests in myriad forms. Symptoms and severity vary from person to person, but all autism spectrum disorders share three core symptoms: impaired social interactions, communication deficits, and excessive repetitive ...

Medical research

Scientists identify new human genes controlling HIV infection

Viruses are parasites. The only way they can grow is by hijacking their hosts. When they infect a human host, viruses use human proteins to multiply and modify the human cells to sustain the infection. At the same time, the ...

Alzheimer's disease & dementia

Predicting Alzheimer's disease-like memory loss before it strikes

For a person with Alzheimer's disease, there's no turning back the clock. By the time she begins to experience memory loss and other worrisome signs, cognitive decline has already set in. And decades of clinical trials have ...

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