Max Delbrück Center for Molecular Medicine

Neuroscience

Studying herpes encephalitis with mini-brains

About 3.7 billion people carry the herpes simplex virus-1 in our nerve cells where it lies quiescent until triggered by stress or injury. When activated, its symptoms are usually mild, limited to cold sores or ulcers in our ...

Neuroscience

Exploring the mechanisms behind swallowing

Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier ...

Diseases, Conditions, Syndromes

Nasal vaccine to prevent COVID-19 passes first tests

Coronaviruses spread primarily through the air. When infected people speak, cough, sneeze or laugh, they expel droplets of saliva containing the virus. Other people then breathe in these airborne pathogens and become infected ...

Neuroscience

How the brain encodes warm and cool

Researchers from the Max Delbrück Center have found a region of the brain that is responsible for our perception of temperature when we touch things. The paper, which appears in Nature, reports the discovery of a "thermal ...

Immunology

How the body's defenses keep their weapons in check

The signaling molecules of the immune system should trigger a response only where necessary. To prevent a life-threatening spread to the rest of the body, connective tissue can absorb these molecules like a sponge. A team ...

Oncology & Cancer

AI analysis of cancer mutations may improve therapy

Cancer has many faces—no wonder, then, that the range of cancer-causing mutations is huge as well. The totality of such genomic alterations in an individual is what experts call a "mutational landscape." These landscapes ...

Genetics

Describing the genes associated with the sixth sense

To perform coordinated movements, we rely on special sensory neurons in our muscles and joints. Without them, the brain wouldn't know what the rest of our body was doing. A team led by Niccolò Zampieri has studied their ...

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