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Immunology

Researchers uncover origin of virus-fighting plasma B cells

Plasma B cells, which move through the body releasing antibodies, are an important component of the body's fight against viral infections and other invaders. They are relatively rare, however, and increasing their ranks is ...

Immunology

In the gut, immunity is a two-way street

In recent years, it has become increasingly clear that many diseases are triggered or maintained by changes in bacterial communities in the gut. However, the general view up into now has been rather simple: bacteria stimulate ...

Medical research

Ensuring the persistence of immune memory

Structures within the lymph nodes known as germinal centers (GCs) help the body to maintain long-term immune defense against foreign threats. The GCs essentially act as sites where antibody-producing B cells undergo a process ...

Oncology & Cancer

Blocking key pathways is a way to defeat cancer stem cells

Scientists from the RIKEN Center for Integrative Medical Sciences in Japan and international collaborators have found that in humanized mice, a cocktail of drugs blocking certain key pathways is effective in eliminating acute ...

Neuroscience

Brain: A 'cingular' strategy for attack and defense

Researchers at the RIKEN Brain Science Institute in Japan have pinpointed specific brain regions related to choosing strategies, specifically deciding to attack an opponent or defend one's position.

Genetics

SUV39H2: A direct genetic link to autism spectrum disorders

New research from the RIKEN Center for Brain Science (CBS) in Japan shows that a deficit in histone methylation could lead to the development of autism spectrum disorders (ASD). A human variant of the SUV39H2 gene led researchers ...

Medical research

A new starring role for astrocytes

Astrocytes, previously thought of as helper cells for neurons, have recently been shown to send signals themselves. The signals are chemical not electrical and astrocytes send them to neurons, vascular cells and other ...

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