A new approach for assisting reproduction in mice when sperm production is faulty has been demonstrated by researchers at RIKEN. It could eventually help human couples who are struggling to conceive by traditional in vitro ...
Sep 12, 2022
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Nestled deep within the body, the epithelial lining of the respiratory system is nonetheless seriously exposed. Its direct contact with environmental air necessitates protective mechanisms that both seal off the respiratory ...
Jan 22, 2013
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In a collaboration between RIKEN's Brain Science Institute and Center for Life Science Technologies in Japan, scientists combined cutting edge methods to obtain a comprehensive catalogue of proteins that are manufactured ...
Jun 5, 2014
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Polycomb-group (PcG) proteins play an important role in controlling gene expression. Complexes containing PcG proteins are thought to inhibit or 'silence' gene activity by localizing to specific targets in the genome and ...
Nov 22, 2013
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A major challenge of systems biology is understanding how phenomena at the cellular scale correlate with activity at the organism level. A concerted effort has been made especially in the brain, as scientists are aiming to ...
Apr 17, 2014
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Scientists at the RIKEN Center for Life Science Technologies have used PET imaging to visualize the distribution in the body of copper, which is deregulated in Menkes disease, a genetic disorder, using a mouse model. This ...
Mar 26, 2014
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A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in establishing a model of the blood-brain barrier using modularized tissue derived from human cells. The "Tissue-in-a-CUBE" ...
Feb 28, 2024
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An international group led by RIKEN in Japan and INSERM in France have found that retroviral long-terminal-repeat (LTR) promoters—a type of repetitive element that are widely distributed in the human genome—are highly ...
Oct 28, 2015
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Local tumor-induced stress in fruit-fly larvae releases a signaling molecule that reprograms the metabolism of the animals, an all-RIKEN team has discovered. If the same thing happens in humans, it could lead to new ways ...
Oct 25, 2023
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Copper is essential for human health, and is critical to the function of a number of enzymes in the body. This important role is highlighted by Menkes disease—an inherited syndrome caused by a genetic mutation that prevents ...
May 16, 2014
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