Page 2 - Rockefeller University

Alzheimer's disease & dementia

'Exhausted' immune cells may drive Alzheimer's

Mice reach the twilight of their lives at around age two, the rough equivalent of 80 in human years. And when researchers introduce specific mutations into mice and then age them up, the mice can grow forgetful and irritable—eventually ...

Medical research

Revealing how an ancient genetic invader inhabits our DNA

Billions of years ago, as primitive lifeforms were becoming more complex, a selfish genetic component became a sort of genome colonizer. Using a copy-and-paste mechanism, this pernicious bit of code replicated and inserted ...

Neuroscience

New method tracks how brain cells age

Hospital nurseries routinely place soft bands around the tiny wrists of newborns that hold important identifying information such as name, sex, mother, and birth date. Researchers at Rockefeller University are taking the ...

Medications

Unlocking how the new Alzheimer's drug lecanemab works

Approved by the FDA earlier this year, the Alzheimer's therapy lecanemab is an antibody that reduces the buildup in the brain of a sticky peptide called amyloid-beta (Aβ), which is thought to be a main driver of the disease. ...

Diseases, Conditions, Syndromes

An immune flaw may cause West Nile virus's deadliest symptoms

Four out of five of people infected with the mosquito-borne West Nile virus (WNV) won't even know it—heartening news when you consider there's no vaccine to prevent the disease nor targeted medications to treat it. However, ...

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