We have a pretty good idea of where memory starts and ends—short-term memories form in the hippocampus and, if the situation calls for it, stabilize into long-term memories in the cortex. But what happens along the winding ...
Mar 30, 2023
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Complex cognition and behavior, in animals and humans alike, hinges on information flowing across a network of deeply interconnected brain cells. For scientists, the scale of that network posed a major obstacle to better ...
Mar 23, 2023
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Our immune systems react most strongly to the viral strains we encountered in our childhoods. Scientists call this original antigenic sin (OAS)—the body's first blush with a virus like influenza or COVID being the "original ...
Jan 18, 2023
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Cells jostling for a spot in a germinal center face a cutthroat admissions process. Formed after exposure to a pathogen or vaccine, germinal centers act as a kind of immune system training academy, helping B cells refine ...
Jan 17, 2023
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If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities. ...
Dec 23, 2022
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Nearly three years into the pandemic, many of us now carry antibodies against the virus—due to an infection or two, a few doses of mRNA vaccine, or a round of monoclonal-antibody treatment. But not all immune responses ...
Dec 6, 2022
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Like the New York City subway system, the DNA in our cells needs to operate around the clock—and it's in constant need of repair. In any given cell at any given time, molecular processes are underway to seal cracks in the ...
Nov 30, 2022
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What drives tumor growth? Is it a few rogue cells imposing their will upon healthy tissue, or diseased tissue bringing out the worst in otherwise peaceable cells? Or is it a back-and-forth, a dialogue between the two? According ...
Nov 30, 2022
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As a rare and lethal liver cancer that disproportionately harms young adults, fibrolamellar carcinoma is nearly incurable. Surgery can remove the tumor, but no existing therapies are capable of reining in the cancer once ...
Nov 10, 2022
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It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others. A new paper published in Nature may explain the ...
Sep 21, 2022
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