Diseases, Conditions, Syndromes

How liver cells become scarring, and worse

Hepatic fibrosis occurs when scar tissue replaces damaged cells in the liver. Over time, accumulating scarring distorts the liver, interferes with its blood supply and may progressively lead to worsening consequences, from ...

Diseases, Conditions, Syndromes

'Humanized' liver in mice reveals roots of chronic diseases

Yale researchers have created a functional "humanized" liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting ...

Immunology

Spatial dimension of macrophage heterogeneity in liver diseases

The hepatic immune landscape is a dynamic compartment, notably composed of highly heterogeneous and adapting myeloid cells. Liver resident macrophage distribution across the tissue and bone-marrow derived monocyte accumulation ...

page 5 from 39