The SARS-CoV-2 delta variant that caused the third wave of COVID-19 in mid-2021 turned out to be more contagious than earlier SARS-CoV-2 variants. In addition, protein mutations in the delta variant were found to significantly ...
Jan 17, 2023
0
43
UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the ...
Dec 27, 2022
0
54
Researchers from the Icahn School of Medicine at Mount Sinai have applied a novel stem cell model to map disease risk variants in human neurons, which could help provide insights into the biological mechanisms that underlie ...
Jun 1, 2022
0
15
Treatment for glioma has long relied on MRI imaging to track tumor markers and treatment response. But findings from a team at the University of Michigan Rogel Cancer Center, led by Carl Koschmann, M.D., pediatric neuro-oncologist ...
Mar 24, 2022
0
30
A team of researchers at Stanford University has found a significant subset of allele-independent regulatory sites that have multiple causal variants in linkage disequilibrium. In their paper published in the journal Science, ...
A study conducted at the University of Helsinki and the Helsinki University Hospital (HUS) suggests that the APOE4 allele may also increase cerebral microhaemorrhages related to COVID-19 and associate with mental fatigue ...
Dec 27, 2021
0
228
The APOE gene—coding for a protein involved in lipid transport and implicated in the clearance of amyloid-beta, one of the proteins that builds up in the brain in Alzheimer's disease—exists in three allelic forms: E4, ...
Sep 29, 2021
1
85
Genetics contributes to the risk of developing Alzheimer's disease, and the APOE gene is the strongest genetic risk factor, specifically the APOE4 allele. However, it has been known for a while that the risk due to the APOE4 ...
Feb 4, 2021
0
15
Autoimmune disease is fundamentally a mystery: whyever should an organism systematically set out to harm itself? Now, researchers at the University of Tsukuba have identified a genetic basis for anti-neutrophil cytoplasmic ...
Nov 4, 2020
0
2
Researchers announce the first robust evidence for the role of the major histocompatibility complex gene HLA-B in penicillin allergy. To identify genetic risk factors for penicillin allergy, the international team of researchers ...
Oct 26, 2020
0
3
