A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken & Ruth Davee Department of Neurology's Division of Movement Disorders, have uncovered previously unknown cellular mechanisms involved ...
Jul 1, 2024
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In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing ...
Jun 17, 2024
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Researchers from the UAB have identified a region in the early aggregates of the alpha-synuclein protein that can be targeted to prevent its conversion into the toxic amyloid fibrils that accumulate in the brains of people ...
May 6, 2024
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Researchers have used computational models to understand what drives the accumulation of alpha-synuclein protein, a key culprit in the development of Parkinson's disease.
Apr 2, 2024
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Although Parkinson's disease has been recognized for more than 100 years, no treatments can slow or halt the disease's progress, let alone cure it. One of the major factors underlying this lack of progress is our relatively ...
Apr 2, 2024
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Microplastics and nanoplastics are everywhere in our environment—including in our oceans and lakes, farmland, and even Arctic ice algae.
Mar 24, 2024
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In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, ...
Mar 20, 2024
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Neurodegenerative diseases, such as Alzheimer's and Parkinson's, present a significant health challenge, affecting over 50 million people globally. One common feature of these diseases is the accumulation of misfolded protein ...
Feb 12, 2024
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While previous studies suggest Parkinson's disease begins in the gut and spreads to the brain, how the process occurs has been elusive. Now, a pre-clinical study led by Duke Health researchers provides new evidence that bolsters ...
Dec 12, 2023
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Research carried out at Oxford's Nuffield Department of Clinical Neurosciences has led to the development of a new blood-based test to identify the pathology that triggers Parkinson's disease before the main symptoms occur. ...
Dec 5, 2023
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