Professor Shimpei Gotoh and Junior Associate Professor Kazuo Takayama teamed up in study to construct a novel in vitro culture system for alveolar and airway epithelial cells, employing a biomaterials engineering method known ...
Mar 29, 2024
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Genetic information collected from seemingly healthy tissue near lung tumors may be a better predictor of whether cancer will come back after treatment than analysis of the tumors themselves, according to new research led ...
Nov 8, 2023
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The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of ...
Oct 17, 2023
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New research performed in mice models at Penn Medicine shows, mechanistically, how the infant lung regenerates cells after injury differently than the adult lung, with alveolar type 1 (AT1) cells reprograming into alveolar ...
May 10, 2021
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Researchers from Children's Hospital of Philadelphia (CHOP) have determined what happens at a cellular level as the lung alveolus forms and allows newborns to breathe air. Understanding this process gives researchers a better ...
Mar 11, 2021
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Using CRISPR gene editing, a team from Children's Hospital of Philadelphia (CHOP) and Penn Medicine have thwarted a lethal lung disease in an animal model in which a harmful mutation causes death within hours after birth. ...
Apr 17, 2019
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Tuberculosis (TB) is the world's deadliest bacterial disease and most commonly affects the lungs. Recent years have seen an increase in drug-resistant TB cases leaving many patients with limited treatment options. The only ...
Mar 25, 2024
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A research team has identified a potential new drug for interstitial lung disease, a condition affecting approximately 4.7 million people worldwide, and validated its protective effects using patient-specific induced pluripotent ...
Oct 12, 2023
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Researchers across the globe continue their endeavors to improve our understanding of the mechanisms underlying COVID-19 infection and the pneumonia and lung damage occasionally associated with it. As part of these endeavors, ...
Jun 29, 2022
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Scientists have developed a lung-on-chip model to study how the body responds to early tuberculosis (TB) infection, according to findings published today in eLife.
Nov 24, 2020
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