Potential therapies for Alzheimer's disease are currently studied using genetically engineered mouse strains that display many of the key features of the disease. Most of these mouse models overexpress the amyloid precursor ...
Jun 6, 2014
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Scientists at NYU Langone Medical Center have identified a compound, called 2-PMAP, in animal studies that reduced by more than half levels of amyloid proteins in the brain associated with Alzheimer's disease. The researchers ...
Jun 3, 2014
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A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's ...
May 20, 2014
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A research team led by the National Neuroscience Institute (NNI) has uncovered a novel function of the Amyloid Precursor Protein (APP), one of the main pathogenic culprits of Alzheimer's disease. This discovery may help researchers ...
Apr 21, 2014
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A team of researchers from Columbia University Medical Center (CUMC), Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called ...
Apr 20, 2014
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In a study published today in Nature Neuroscience, a group of researchers led by Takaomi Saido of the RIKEN Brain Science Institute in Japan have reported the creation of two new mouse models of Alzheimer's disease that may ...
Apr 13, 2014
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Researchers have shown that they can detect tiny, misfolded protein fragments in cerebrospinal fluid taken from patients. Such fragments have been suggested to be the main culprit in Alzheimer's disease. The findings reported ...
Mar 20, 2014
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Why do neurodegenerative diseases such as Alzheimer's affect only the elderly? Why do some people live to be over 100 with intact cognitive function while others develop dementia decades earlier?
Mar 19, 2014
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People who experience chronic sleep disturbance—either through their work, insomnia or other reasons—could face an earlier onset of dementia and Alzheimer's, according to a new pre-clinical study by researchers at Temple ...
Mar 18, 2014
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Reelin, a crucial protein for adult brain plasticity, recovers cognitive functions in mice with Alzheimer's disease. This is one of the main results of an article published on the journal Nature Communications, co-led by ...
Mar 7, 2014
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