Alzheimer's disease & dementia

Structural analysis of relevant drug targets for Alzheimer's disease

Alzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant. In AD, the beta-amyloid precursor protein (β-APP) that ...

Alzheimer's disease & dementia

Focus on Alzheimer's disease shifts to prevention

It has been 111 years since Auguste D. became the first person described with what is now called Alzheimer's disease. German psychiatrist Alois Alzheimer, for whom the disease is named, first publically reported his observations ...

Alzheimer's disease & dementia

Never before seen images of early stage Alzheimer's disease

Researchers at Lund University in Sweden have used the MAX IV synchrotron in Lund – the strongest of its kind in the world - to produce images that predate the formation of toxic clumps of beta-amyloid, the protein believed ...

Alzheimer's disease & dementia

Gut bacteria may play a role in Alzheimer's disease

New research from Lund University in Sweden has shown that intestinal bacteria can accelerate the development of Alzheimer's disease. According to the researchers behind the study, the results open up the door to new opportunities ...

Alzheimer's disease & dementia

Roots of Alzheimer's disease can extend as far back as the womb

Biochemical reactions that cause Alzheimer's disease could begin in the womb or just after birth if the fetus or newborn does not get enough vitamin A, according to new research from the University of British Columbia.

Alzheimer's disease & dementia

New drug SAK3 may offer hope to Alzheimer's disease patients

Acetylcholine is a neurotransmitter in the brain that plays an important role in controlling attention and cognition. Acetylcholine system dysfunction is believed to be one of the causes of Alzheimer's disease (AD) and vascular ...

Alzheimer's disease & dementia

Landmark Alzheimer's prevention trial to evaluate third drug

An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial - already underway - aimed at finding treatments to prevent ...

Alzheimer's disease & dementia

Alzheimer's protein plaques may also harm the heart

(HealthDay)—Protein fragments that form plaques in the brains of Alzheimer's patients might also stiffen their heart muscle and increase their risk of heart failure, a new study reports.

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