Most human cells have 23 pairs of chromosomes. Any deviation from this number can be fatal for cells, and several genetic disorders, such as Down syndrome, are caused by abnormal numbers of chromosomes.
May 13, 2019
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Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the researchers, suggest that selectively ...
Jul 6, 2023
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The vast majority of cancer cells have too few or too many copies of some chromosomes, a state known as aneuploidy. But for decades, researchers have debated whether aneuploidy promotes the growth of cancers, or is simply ...
Jun 29, 2023
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A woman's risk of suffering one of the most common types of miscarriages can be predicted based on a specialized analysis of her genome, according to a Rutgers University study.
Jun 13, 2022
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Scientists have found a genetic mutation that results in cancer cells being able to tolerate having an abnormal number of chromosomes—a condition which normally kills cells—allowing them to adapt to their environment ...
May 9, 2022
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What makes cancer cells different from ordinary cells? Can these differences be used to strike at them and paralyze their activity? This basic question has bothered cancer researchers since the mid-19th century. The search ...
Jan 27, 2021
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Cancer cells are notorious for their genetic disarray. A tumor cell can contain an abundance of DNA mutations and most have the wrong number of chromosomes. A missing or extra copy of a single chromosome creates an imbalance ...
Feb 24, 2020
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Scientists have identified a genetic mutation that causes a childhood kidney cancer called Wilms' tumour.
May 30, 2017
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Aneuploidy is a condition in which cells contain an abnormal number of chromosomes, and is known to be the cause of many types of cancer and genetic disorders, including Down Syndrome. The condition is also the leading cause ...
Apr 6, 2017
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(Medical Xpress)—A team of researchers at Stanford University has found a gene that increases the rate of maternal aneuploidy in embryos. In their paper published in the journal Science, the team describes how they used ...
Aneuploidy is an abnormal number of chromosomes, and is a type of chromosome abnormality. An extra or missing chromosome is a common cause of genetic disorders (birth defects). Some cancer cells also have abnormal numbers of chromosomes. Aneuploidy occurs during cell division when the chromosomes do not separate properly between the two cells. Chromosome abnormalities occur in 1 of 160 live births. The most common extra chromosomes among live births are 21, 18 and 13.
Different species have different numbers of normal chromosomes and thus the term "aneuploidy" refers to the chromosome number being different for that species.
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